Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0006402 | biological_process | mRNA catabolic process |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0008859 | molecular_function | exoribonuclease II activity |
| A | 0016070 | biological_process | RNA metabolic process |
| A | 0016078 | biological_process | tRNA decay |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004527 | molecular_function | exonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006401 | biological_process | RNA catabolic process |
| B | 0006402 | biological_process | mRNA catabolic process |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0008859 | molecular_function | exoribonuclease II activity |
| B | 0016070 | biological_process | RNA metabolic process |
| B | 0016078 | biological_process | tRNA decay |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004527 | molecular_function | exonuclease activity |
| C | 0004540 | molecular_function | RNA nuclease activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006401 | biological_process | RNA catabolic process |
| C | 0006402 | biological_process | mRNA catabolic process |
| C | 0008408 | molecular_function | 3'-5' exonuclease activity |
| C | 0008859 | molecular_function | exoribonuclease II activity |
| C | 0016070 | biological_process | RNA metabolic process |
| C | 0016078 | biological_process | tRNA decay |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0004527 | molecular_function | exonuclease activity |
| D | 0004540 | molecular_function | RNA nuclease activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006401 | biological_process | RNA catabolic process |
| D | 0006402 | biological_process | mRNA catabolic process |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0008859 | molecular_function | exoribonuclease II activity |
| D | 0016070 | biological_process | RNA metabolic process |
| D | 0016078 | biological_process | tRNA decay |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN A 1001 |
| Chain | Residue |
| A | ASP201 |
| A | ASP209 |
| A | ASP210 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN B 1002 |
| Chain | Residue |
| B | ASP201 |
| B | ASP209 |
| B | ASP210 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN C 1003 |
| Chain | Residue |
| C | ASP201 |
| C | ASP209 |
| C | ASP210 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN D 1004 |
| Chain | Residue |
| D | ASP201 |
| D | ASP209 |
| D | ASP210 |
Functional Information from PROSITE/UniProt
| site_id | PS01175 |
| Number of Residues | 25 |
| Details | RIBONUCLEASE_II Ribonuclease II family signature. HFGLglea.YAtWTSPIRKYgDminH |
| Chain | Residue | Details |
| A | HIS484-HIS508 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS501 | |
| B | LYS501 | |
| C | LYS501 | |
| D | LYS501 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 338 |
| Chain | Residue | Details |
| A | ASP201 | metal ligand |
| A | ASP207 | metal ligand |
| A | ASP209 | activator, electrostatic stabiliser, increase nucleophilicity |
| A | ASP210 | metal ligand |
| A | TYR313 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ARG500 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 338 |
| Chain | Residue | Details |
| B | ASP201 | metal ligand |
| B | ASP207 | metal ligand |
| B | ASP209 | activator, electrostatic stabiliser, increase nucleophilicity |
| B | ASP210 | metal ligand |
| B | TYR313 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ARG500 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 338 |
| Chain | Residue | Details |
| C | ASP201 | metal ligand |
| C | ASP207 | metal ligand |
| C | ASP209 | activator, electrostatic stabiliser, increase nucleophilicity |
| C | ASP210 | metal ligand |
| C | TYR313 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | ARG500 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 6 |
| Details | M-CSA 338 |
| Chain | Residue | Details |
| D | ASP201 | metal ligand |
| D | ASP207 | metal ligand |
| D | ASP209 | activator, electrostatic stabiliser, increase nucleophilicity |
| D | ASP210 | metal ligand |
| D | TYR313 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | ARG500 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
