2I7T

Structure of human CPSF-73

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 481

Chain	Residue
A	ASP75
A	HIS76
A	ASP179
A	HIS418
A	ZN482
A	SO4491

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 482

Chain	Residue
A	ASP179
A	ZN481
A	SO4491
A	HIS71
A	HIS73
A	HIS158

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 491

Chain	Residue
A	HIS73
A	ASP75
A	HIS158
A	ASP179
A	HIS396
A	HIS418
A	ZN481
A	ZN482

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255

Chain	Residue	Details
A	HIS396

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:17128255, ECO:0007744|PDB:2I7T, ECO:0007744|PDB:2I7V

Chain	Residue	Details
A	HIS71
A	HIS73
A	ASP75
A	HIS76
A	HIS158
A	ASP179
A	HIS418

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895

Chain	Residue	Details
A	SER2

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 2bmi

Chain	Residue	Details
A	ASP179
A	ASP75

---