2I54
Phosphomannomutase from Leishmania mexicana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004615 | molecular_function | phosphomannomutase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006013 | biological_process | mannose metabolic process |
| A | 0006487 | biological_process | protein N-linked glycosylation |
| A | 0009298 | biological_process | GDP-mannose biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004615 | molecular_function | phosphomannomutase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006013 | biological_process | mannose metabolic process |
| B | 0006487 | biological_process | protein N-linked glycosylation |
| B | 0009298 | biological_process | GDP-mannose biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004615 | molecular_function | phosphomannomutase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006013 | biological_process | mannose metabolic process |
| C | 0006487 | biological_process | protein N-linked glycosylation |
| C | 0009298 | biological_process | GDP-mannose biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1001 |
| Chain | Residue |
| A | PHE118 |
| A | PHE118 |
| A | VAL119 |
| A | VAL119 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1002 |
| Chain | Residue |
| B | PHE118 |
| B | VAL119 |
| C | PHE118 |
| C | VAL119 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 2001 |
| Chain | Residue |
| B | ASP12 |
| B | ASP207 |
| B | ASP10 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 2002 |
| Chain | Residue |
| A | ASP10 |
| A | ASP12 |
| A | ASP207 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 2003 |
| Chain | Residue |
| C | ASP10 |
| C | ASP12 |
| C | ASP207 |
| C | HOH3030 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CIT A 3001 |
| Chain | Residue |
| A | ARG133 |
| A | ARG140 |
| A | GLY175 |
| A | GLN176 |
| A | ILE177 |
| A | SER178 |
| A | HOH3036 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CIT B 3002 |
| Chain | Residue |
| B | SER46 |
| B | LYS50 |
| B | ARG122 |
| B | ASN127 |
| B | ARG133 |
| B | ARG140 |
| B | GLY174 |
| B | GLY175 |
| B | GLN176 |
| B | ILE177 |
| B | SER178 |
| B | ASP180 |
| B | HOH3025 |
| B | HOH3038 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CIT C 3003 |
| Chain | Residue |
| C | SER46 |
| C | LYS50 |
| C | ARG122 |
| C | ASN127 |
| C | ARG133 |
| C | ARG140 |
| C | GLY174 |
| C | GLY175 |
| C | GLN176 |
| C | ILE177 |
| C | SER178 |
| C | ASP180 |
| C | HOH3022 |
| C | HOH3084 |
| C | HOH3085 |
