2I2Q
Fission Yeast cofilin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0003785 | molecular_function | actin monomer binding |
| A | 0003789 | molecular_function | actin filament severing activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0016363 | cellular_component | nuclear matrix |
| A | 0030042 | biological_process | actin filament depolymerization |
| A | 0030479 | cellular_component | actin cortical patch |
| A | 0031097 | cellular_component | medial cortex |
| A | 0032153 | cellular_component | cell division site |
| A | 0051014 | biological_process | actin filament severing |
| A | 0051015 | molecular_function | actin filament binding |
| A | 0051286 | cellular_component | cell tip |
| A | 0051301 | biological_process | cell division |
| A | 0071944 | cellular_component | cell periphery |
| A | 0110085 | cellular_component | mitotic actomyosin contractile ring |
| A | 0140775 | molecular_function | actin filament debranching activity |
| A | 1903475 | biological_process | mitotic actomyosin contractile ring assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | SER2 |
| A | PHE3 |
| A | SER4 |
| A | THR105 |
| A | ARG108 |
| A | HOH1004 |
| A | HOH1037 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2002 |
| Chain | Residue |
| A | ILE93 |
| A | HOH1033 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE LDA A 900 |
| Chain | Residue |
| A | PHE50 |
| A | LEU54 |
| A | LEU57 |
| A | ASP121 |
| A | EDO304 |
| A | EDO304 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 301 |
| Chain | Residue |
| A | GLU42 |
| A | ASP56 |
| A | PRO58 |
| A | ARG63 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 302 |
| Chain | Residue |
| A | SER45 |
| A | THR46 |
| A | HOH1018 |
| A | HOH1087 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 303 |
| Chain | Residue |
| A | VAL8 |
| A | PRO10 |
| A | LEU13 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | LDA900 |
| A | LDA900 |
