2I0Q
Crystal structure of a telomere single-strand DNA-protein complex from O. nova with full-length alpha and beta telomere proteins
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0000781 | cellular_component | chromosome, telomeric region |
| A | 0000782 | cellular_component | telomere cap complex |
| A | 0000783 | cellular_component | nuclear telomere cap complex |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0010521 | molecular_function | telomerase inhibitor activity |
| A | 0016233 | biological_process | telomere capping |
| A | 0032210 | biological_process | regulation of telomere maintenance via telomerase |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0043047 | molecular_function | single-stranded telomeric DNA binding |
| A | 0098505 | molecular_function | G-rich strand telomeric DNA binding |
| B | 0000781 | cellular_component | chromosome, telomeric region |
| B | 0000782 | cellular_component | telomere cap complex |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0016233 | biological_process | telomere capping |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042162 | molecular_function | telomeric DNA binding |
| B | 0043047 | molecular_function | single-stranded telomeric DNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 496 |
| Chain | Residue |
| A | THR157 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 497 |
| Chain | Residue |
| A | ARG481 |
| A | ASN483 |
| A | GLY484 |
| B | LYS182 |
| B | GLY183 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 498 |
| Chain | Residue |
| B | ARG152 |
| A | GLN423 |
| A | HOH635 |
| B | GLN149 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 499 |
| Chain | Residue |
| A | THR126 |
| A | ARG128 |
| A | ASN137 |
| A | LYS447 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 500 |
| Chain | Residue |
| A | HIS234 |
| A | GLU235 |
| A | VAL334 |
| A | TYR474 |
| A | HOH553 |
| A | HOH615 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 501 |
| Chain | Residue |
| A | SER208 |
| A | TYR211 |
| A | HOH647 |
| A | HOH702 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 502 |
| Chain | Residue |
| A | THR82 |
| A | LEU83 |
| A | TYR84 |
| A | LEU85 |
| A | ASP96 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 386 |
| Chain | Residue |
| A | GLU379 |
| A | PRO380 |
| A | SER381 |
| B | GLY166 |
| B | ASP167 |
| B | ASN168 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | ARG370 |
| A | GLN372 |
