2HVQ

Structure of Adenylated full-length T4 RNA Ligase 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003972	molecular_function	RNA ligase (ATP) activity
A	0005524	molecular_function	ATP binding
A	0016874	molecular_function	ligase activity
A	0042245	biological_process	RNA repair
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 335

Chain	Residue
A	APK35
A	HIS37
A	GLU204
A	HOH391
A	HOH410

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 336

Chain	Residue
A	HOH352
A	ILE162
A	LEU164
A	ASN166
A	TYR206

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_04150","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17018278","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04150","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14962393","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17018278","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14962393","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17018278","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04150","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14962393","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04150","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17018278","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Interaction with RNA","evidences":[{"source":"HAMAP-Rule","id":"MF_04150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---