Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0042802 | molecular_function | identical protein binding |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 501 |
Chain | Residue |
A | LEU38 |
A | GLY40 |
B | LYS155 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 502 |
Chain | Residue |
A | VAL11 |
A | THR12 |
B | LYS107 |
site_id | AC3 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE 017 A 201 |
Chain | Residue |
A | ASP29 |
A | ASP30 |
A | GLY48 |
A | GLY49 |
A | ILE50 |
A | PRO81 |
A | VAL82 |
A | ILE84 |
A | HOH1118 |
A | HOH1211 |
B | ASP125 |
B | GLY127 |
B | ALA128 |
B | ASP129 |
B | ASP130 |
B | VAL132 |
B | GLY148 |
B | GLY149 |
B | ILE150 |
B | PRO181 |
B | ILE184 |
A | ASP25 |
A | GLY27 |
A | ALA28 |
site_id | AC4 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE 017 B 203 |
Chain | Residue |
A | TRP6 |
A | ARG41 |
A | HOH1104 |
A | HOH1136 |
A | HOH1208 |
B | TRP142 |
B | PRO144 |
B | LYS145 |
B | LYS155 |
B | VAL156 |
B | ARG157 |
B | GLY168 |
B | VAL177 |
B | GLY178 |
B | GLN192 |
B | GLY194 |
B | HOH1017 |
B | HOH1076 |
B | HOH1116 |
B | HOH1175 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE DMS B 801 |
Chain | Residue |
A | TRP6 |
B | TRP142 |
B | ARG157 |
B | HOH1017 |
B | HOH1175 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
Chain | Residue | Details |
A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | THR26 | |
B | THR126 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Cleavage; by viral protease |
Chain | Residue | Details |
A | PRO1 | |
B | PRO101 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a30 |
Chain | Residue | Details |
A | ASP25 | |
A | THR26 | |
B | THR126 | |
B | ASP125 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a30 |
Chain | Residue | Details |
A | ASP25 | |
B | ASP125 | |