2HR9

Solution structure of human translationally controlled tumor protein

Replaces:  1Y41

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000922	cellular_component	spindle pole
A	0003723	molecular_function	RNA binding
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005771	cellular_component	multivesicular body
A	0005829	cellular_component	cytosol
A	0005881	cellular_component	cytoplasmic microtubule
A	0006816	biological_process	calcium ion transport
A	0006874	biological_process	intracellular calcium ion homeostasis
A	0009615	biological_process	response to virus
A	0042981	biological_process	regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
A	0070062	cellular_component	extracellular exosome
A	1902230	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Functional Information from PROSITE/UniProt

site_id	PS01002
Number of Residues	11
Details	TCTP_1 Translationally controlled tumor protein (TCTP) domain signature 1. IGGNASAEGPE

Chain	Residue	Details
A	ILE48-GLU58

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site_id	PS01003
Number of Residues	23
Details	TCTP_2 Translationally controlled tumor protein (TCTP) domain signature 2. FknyqFFIGEnmnp...DGmVAlldY

Chain	Residue	Details
A	PHE129-TYR151

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PLK1 => ECO:0000269|PubMed:12167714, ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER46

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER53

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PLK1 => ECO:0000269|PubMed:12167714

Chain	Residue	Details
A	SER64

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