Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1001 |
| Chain | Residue |
| B | THR417 |
| B | MET420 |
| B | PRO421 |
| B | PHE422 |
| B | GLY423 |
| B | GLU424 |
| B | SER425 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1002 |
| Chain | Residue |
| A | LYS124 |
| A | TRP14 |
| A | ASN121 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1004 |
| Chain | Residue |
| A | LEU311 |
| A | TYR312 |
| A | MET313 |
| A | ASP314 |
| A | HOH1350 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 1005 |
| Chain | Residue |
| A | ARG392 |
| A | GLU394 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 1006 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1007 |
| Chain | Residue |
| B | TRP419 |
| B | MET420 |
| B | PRO421 |
| B | HOH1567 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 1008 |
| Chain | Residue |
| A | ALA230 |
| A | GLU231 |
| B | LEU146 |
| B | ALA147 |
| B | GLY148 |
| B | LYS308 |
| B | HOH1502 |
| B | HOH1538 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1009 |
| Chain | Residue |
| A | HIS408 |
| B | ASP405 |
| B | ALA407 |
| B | HIS408 |
| B | HOH1336 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1010 |
| Chain | Residue |
| A | SER267 |
| A | HIS408 |
| A | LYS412 |
| A | ASP415 |
| A | EDO1019 |
| A | HOH1498 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 1011 |
| Chain | Residue |
| A | VAL95 |
| A | ARG138 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1012 |
| Chain | Residue |
| B | TRP14 |
| B | LYS15 |
| B | ASN121 |
| B | LYS124 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1013 |
| Chain | Residue |
| B | ARG392 |
| B | GLU394 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1014 |
| Chain | Residue |
| B | PRO94 |
| B | VAL95 |
| B | PEG1106 |
| B | HOH1389 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1015 |
| Chain | Residue |
| B | GLU307 |
| B | LYS308 |
| B | LEU310 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1016 |
| Chain | Residue |
| A | GLY66 |
| A | PRO421 |
| A | HOH1297 |
| A | HOH1325 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1017 |
| Chain | Residue |
| A | ARG433 |
| A | SER434 |
| A | ALA437 |
| A | HOH1471 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1018 |
| Chain | Residue |
| B | ALA13 |
| B | ALA16 |
| B | LYS17 |
| B | ILE18 |
| B | TRP256 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1019 |
| Chain | Residue |
| A | SER267 |
| A | EDO1010 |
| A | HOH1261 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1020 |
| Chain | Residue |
| A | GLU410 |
| A | PHE413 |
| A | LYS414 |
| A | SER425 |
| A | GLY426 |
| A | HOH1397 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX A 1201 |
| Chain | Residue |
| A | SER92 |
| A | GLY98 |
| A | HIS99 |
| A | UNX1202 |
| A | UNX1203 |
| A | UNX1204 |
| A | UNX1209 |
| A | UNX1211 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX A 1202 |
| Chain | Residue |
| A | UNX1201 |
| A | UNX1203 |
| A | UNX1204 |
| A | UNX1206 |
| A | UNX1208 |
| A | UNX1210 |
| A | UNX1211 |
| A | UNX1212 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UNX A 1203 |
| Chain | Residue |
| A | UNX1208 |
| A | UNX1209 |
| A | UNX1211 |
| A | UNX1212 |
| A | SER92 |
| A | THR374 |
| A | UNX1201 |
| A | UNX1202 |
| A | UNX1204 |
| site_id | CC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UNX A 1204 |
| Chain | Residue |
| A | HIS99 |
| A | UNX1201 |
| A | UNX1202 |
| A | UNX1203 |
| A | UNX1205 |
| A | UNX1206 |
| A | UNX1207 |
| A | UNX1208 |
| A | UNX1211 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE UNX A 1205 |
| Chain | Residue |
| A | HIS99 |
| A | HIS150 |
| A | UNX1204 |
| A | UNX1206 |
| A | UNX1207 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE UNX A 1206 |
| Chain | Residue |
| A | TYR145 |
| A | PHE193 |
| A | UNX1202 |
| A | UNX1204 |
| A | UNX1205 |
| A | UNX1207 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE UNX A 1207 |
| Chain | Residue |
| A | HIS99 |
| A | HIS150 |
| A | LYS198 |
| A | UNX1204 |
| A | UNX1205 |
| A | UNX1206 |
| A | HOH1531 |
| site_id | CC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX A 1208 |
| Chain | Residue |
| A | ARG97 |
| A | SER372 |
| A | GLY373 |
| A | UNX1202 |
| A | UNX1203 |
| A | UNX1204 |
| A | UNX1210 |
| A | UNX1212 |
| site_id | DC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UNX A 1209 |
| Chain | Residue |
| A | SER92 |
| A | PHE93 |
| A | PRO94 |
| A | ARG97 |
| A | THR374 |
| A | UNX1201 |
| A | UNX1203 |
| A | UNX1211 |
| A | UNX1212 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE UNX A 1210 |
| Chain | Residue |
| A | CYS271 |
| A | ALA273 |
| A | UNX1202 |
| A | UNX1208 |
| A | UNX1212 |
| A | HOH1239 |
| site_id | DC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UNX A 1211 |
| Chain | Residue |
| A | SER92 |
| A | HIS99 |
| A | UNX1201 |
| A | UNX1202 |
| A | UNX1203 |
| A | UNX1204 |
| A | UNX1209 |
| A | UNX1212 |
| A | HOH1530 |
| site_id | DC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX A 1212 |
| Chain | Residue |
| A | GLY373 |
| A | THR374 |
| A | UNX1202 |
| A | UNX1203 |
| A | UNX1208 |
| A | UNX1209 |
| A | UNX1210 |
| A | UNX1211 |
| site_id | DC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX B 1221 |
| Chain | Residue |
| B | PHE193 |
| B | PEG1102 |
| B | UNX1222 |
| B | UNX1223 |
| B | UNX1224 |
| B | UNX1225 |
| B | UNX1226 |
| B | HOH1569 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE UNX B 1222 |
| Chain | Residue |
| B | TYR145 |
| B | PEG1102 |
| B | UNX1221 |
| B | UNX1223 |
| B | UNX1224 |
| B | UNX1225 |
| B | UNX1226 |
| site_id | DC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE UNX B 1223 |
| Chain | Residue |
| B | HIS99 |
| B | HIS150 |
| B | LYS198 |
| B | UNX1221 |
| B | UNX1222 |
| B | UNX1224 |
| B | UNX1225 |
| B | UNX1226 |
| B | UNX1227 |
| B | HOH1569 |
| site_id | DC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE UNX B 1224 |
| Chain | Residue |
| B | HIS99 |
| B | TYR145 |
| B | HIS150 |
| B | PHE193 |
| B | UNX1221 |
| B | UNX1222 |
| B | UNX1223 |
| B | UNX1225 |
| B | UNX1226 |
| B | UNX1227 |
| site_id | DC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX B 1225 |
| Chain | Residue |
| B | HIS99 |
| B | UNX1221 |
| B | UNX1222 |
| B | UNX1223 |
| B | UNX1224 |
| B | UNX1226 |
| B | UNX1227 |
| B | HOH1539 |
| site_id | EC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE UNX B 1226 |
| Chain | Residue |
| B | TYR145 |
| B | HIS150 |
| B | UNX1221 |
| B | UNX1222 |
| B | UNX1223 |
| B | UNX1224 |
| B | UNX1225 |
| B | UNX1227 |
| site_id | EC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UNX B 1227 |
| Chain | Residue |
| B | ARG97 |
| B | GLY98 |
| B | HIS150 |
| B | PRO151 |
| B | THR152 |
| B | UNX1223 |
| B | UNX1224 |
| B | UNX1225 |
| B | UNX1226 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 1101 |
| Chain | Residue |
| A | ARG431 |
| A | THR443 |
| A | GLN445 |
| A | HOH1305 |
| site_id | EC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PEG B 1102 |
| Chain | Residue |
| B | SER92 |
| B | PHE93 |
| B | PRO94 |
| B | ARG97 |
| B | GLY98 |
| B | CYS271 |
| B | TYR272 |
| B | PRO309 |
| B | SER372 |
| B | GLY373 |
| B | THR374 |
| B | UNX1221 |
| B | UNX1222 |
| B | HOH1272 |
| B | HOH1539 |
| site_id | EC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEG B 1103 |
| Chain | Residue |
| B | GLU43 |
| B | HIS85 |
| B | ALA86 |
| B | ASP88 |
| B | LYS198 |
| B | PRO199 |
| B | THR318 |
| B | GLU319 |
| B | LYS322 |
| B | HOH1241 |
| site_id | EC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 1104 |
| Chain | Residue |
| B | GLU307 |
| B | ARG362 |
| B | PHE363 |
| B | ASP364 |
| B | HOH1374 |
| B | HOH1455 |
| B | HOH1557 |
| site_id | EC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 1105 |
| Chain | Residue |
| B | LEU311 |
| B | TYR312 |
| B | MET313 |
| B | ASP314 |
| B | HOH1361 |
| B | HOH1390 |
| site_id | EC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG B 1106 |
| Chain | Residue |
| B | PRO94 |
| B | VAL95 |
| B | ARG97 |
| B | GLY137 |
| B | GLY141 |
| B | EDO1014 |
| B | HOH1506 |
| B | HOH1507 |
