2HLN
L-asparaginase from Erwinia carotovora in complex with glutamic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004067 | molecular_function | asparaginase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006528 | biological_process | asparagine metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004067 | molecular_function | asparaginase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006528 | biological_process | asparagine metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004067 | molecular_function | asparaginase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006528 | biological_process | asparagine metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004067 | molecular_function | asparaginase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0006528 | biological_process | asparagine metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| E | 0004067 | molecular_function | asparaginase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0006528 | biological_process | asparagine metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| F | 0004067 | molecular_function | asparaginase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0006520 | biological_process | amino acid metabolic process |
| F | 0006528 | biological_process | asparagine metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| G | 0004067 | molecular_function | asparaginase activity |
| G | 0005829 | cellular_component | cytosol |
| G | 0006520 | biological_process | amino acid metabolic process |
| G | 0006528 | biological_process | asparagine metabolic process |
| G | 0016787 | molecular_function | hydrolase activity |
| H | 0004067 | molecular_function | asparaginase activity |
| H | 0005829 | cellular_component | cytosol |
| H | 0006520 | biological_process | amino acid metabolic process |
| H | 0006528 | biological_process | asparagine metabolic process |
| H | 0016787 | molecular_function | hydrolase activity |
| I | 0004067 | molecular_function | asparaginase activity |
| I | 0005829 | cellular_component | cytosol |
| I | 0006520 | biological_process | amino acid metabolic process |
| I | 0006528 | biological_process | asparagine metabolic process |
| I | 0016787 | molecular_function | hydrolase activity |
| J | 0004067 | molecular_function | asparaginase activity |
| J | 0005829 | cellular_component | cytosol |
| J | 0006520 | biological_process | amino acid metabolic process |
| J | 0006528 | biological_process | asparagine metabolic process |
| J | 0016787 | molecular_function | hydrolase activity |
| K | 0004067 | molecular_function | asparaginase activity |
| K | 0005829 | cellular_component | cytosol |
| K | 0006520 | biological_process | amino acid metabolic process |
| K | 0006528 | biological_process | asparagine metabolic process |
| K | 0016787 | molecular_function | hydrolase activity |
| L | 0004067 | molecular_function | asparaginase activity |
| L | 0005829 | cellular_component | cytosol |
| L | 0006520 | biological_process | amino acid metabolic process |
| L | 0006528 | biological_process | asparagine metabolic process |
| L | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU A 3350 |
| Chain | Residue |
| A | GLY14 |
| A | HOH3576 |
| A | THR15 |
| A | GLY61 |
| A | SER62 |
| A | GLU63 |
| A | GLY94 |
| A | THR95 |
| A | ASP96 |
| A | HOH3359 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU J 3351 |
| Chain | Residue |
| J | GLY14 |
| J | THR15 |
| J | GLY61 |
| J | SER62 |
| J | GLU63 |
| J | GLY94 |
| J | THR95 |
| J | ASP96 |
| J | ALA120 |
| J | HOH3374 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU E 3352 |
| Chain | Residue |
| E | THR15 |
| E | GLY61 |
| E | SER62 |
| E | GLU63 |
| E | GLY94 |
| E | THR95 |
| E | ASP96 |
| E | ALA120 |
| E | HOH3406 |
| E | HOH3448 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU F 3353 |
| Chain | Residue |
| F | GLY14 |
| F | THR15 |
| F | GLY61 |
| F | SER62 |
| F | GLU63 |
| F | GLY94 |
| F | THR95 |
| F | ASP96 |
| F | ALA120 |
| F | HOH3366 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GLU C 3354 |
| Chain | Residue |
| C | GLY14 |
| C | THR15 |
| C | GLY61 |
| C | SER62 |
| C | GLU63 |
| C | GLY94 |
| C | THR95 |
| C | ASP96 |
| C | ALA120 |
| C | HOH3432 |
| C | HOH3483 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GLU D 3355 |
| Chain | Residue |
| D | GLY14 |
| D | THR15 |
| D | GLY61 |
| D | SER62 |
| D | GLU63 |
| D | GLY94 |
| D | THR95 |
| D | ASP96 |
| D | ALA120 |
| D | HOH3381 |
| D | HOH3388 |
| D | HOH3400 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GLU G 3356 |
| Chain | Residue |
| G | GLY14 |
| G | THR15 |
| G | GLY61 |
| G | SER62 |
| G | GLU63 |
| G | GLY94 |
| G | THR95 |
| G | ASP96 |
| G | ALA120 |
| G | HOH3403 |
| G | HOH3459 |
| G | HOH3489 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GLU H 3357 |
| Chain | Residue |
| H | GLY14 |
| H | THR15 |
| H | GLY61 |
| H | SER62 |
| H | GLU63 |
| H | GLY94 |
| H | THR95 |
| H | ASP96 |
| H | ALA120 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GLU I 3358 |
| Chain | Residue |
| I | GLY14 |
| I | THR15 |
| I | GLY61 |
| I | SER62 |
| I | GLU63 |
| I | GLY94 |
| I | THR95 |
| I | ASP96 |
| I | ALA120 |
| I | HOH3420 |
| I | HOH3453 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GLU B 3359 |
| Chain | Residue |
| B | GLU63 |
| B | GLY94 |
| B | THR95 |
| B | ASP96 |
| B | ALA120 |
| B | HOH3362 |
| B | HOH3399 |
| B | HOH3464 |
| B | GLY14 |
| B | THR15 |
| B | GLY61 |
| B | SER62 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GLU K 3360 |
| Chain | Residue |
| K | GLY14 |
| K | THR15 |
| K | GLY61 |
| K | SER62 |
| K | GLU63 |
| K | GLY94 |
| K | THR95 |
| K | ASP96 |
| K | ALA120 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GLU L 3361 |
| Chain | Residue |
| L | THR15 |
| L | GLY61 |
| L | SER62 |
| L | GLU63 |
| L | GLY94 |
| L | THR95 |
| L | ASP96 |
| L | ALA120 |
| L | HOH3421 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG K 2001 |
| Chain | Residue |
| I | ILE222 |
| I | TYR224 |
| I | HOH3415 |
| K | ILE222 |
| K | ILE223 |
| K | TYR224 |
| K | TYR226 |
| K | PRO230 |
| K | MET233 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 2002 |
| Chain | Residue |
| A | VAL202 |
| A | ALA326 |
| A | HOH3380 |
| A | HOH3462 |
| A | HOH3511 |
| G | GLU231 |
| G | ALA261 |
| G | LYS265 |
| G | PEG2006 |
| site_id | BC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG B 2003 |
| Chain | Residue |
| B | ILE222 |
| B | ILE223 |
| B | TYR224 |
| B | TYR226 |
| B | PRO230 |
| B | MET233 |
| F | ILE222 |
| F | ILE223 |
| F | TYR224 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG C 2004 |
| Chain | Residue |
| A | TYR323 |
| A | HOH3446 |
| C | PRO218 |
| C | ALA219 |
| C | HOH3546 |
| C | HOH3548 |
| G | ASP228 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG K 2005 |
| Chain | Residue |
| K | PRO218 |
| K | ALA219 |
| K | HOH3506 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG G 2006 |
| Chain | Residue |
| A | ASP200 |
| A | PEG2002 |
| F | ASN146 |
| F | ARG198 |
| G | ALA261 |
| G | ARG264 |
| G | LYS265 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG K 2007 |
| Chain | Residue |
| K | ASP200 |
| K | LYS201 |
| K | VAL202 |
| K | HIS203 |
| K | ARG206 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG K 2008 |
| Chain | Residue |
| K | THR205 |
| K | ARG206 |
| K | HOH3499 |
Functional Information from PROSITE/UniProt
