2HI8
human formylglycine generating enzyme, C336S mutant, bromide co-crystallization
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:7628016 |
| Chain | Residue | Details |
| P | CYS1 | |
| X | ASN259 | |
| X | ILE260 | |
| X | ASP273 | |
| X | PHE275 | |
| X | ASN293 | |
| X | GLY296 | |
| X | ALA298 | |
| X | GLU300 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: via 3-oxoalanine => ECO:0000269|PubMed:12888274, ECO:0007744|PDB:1N2K |
| Chain | Residue | Details |
| P | CYS1 | |
| X | CYS341 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: 3-oxoalanine (Cys) => ECO:0000269|PubMed:7628016, ECO:0000269|PubMed:9342345 |
| Chain | Residue | Details |
| P | CYS1 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 158 |
| Chain | Residue | Details |
| P | CYS1 | electrofuge, electrophile, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, metal ligand, nucleophile, proton acceptor, proton donor, proton relay |
| P | ARG5 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
