Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2HET

Non-myristoylated bovine recoverin (truncated at C-terminus) with calcium bound to EF-hand 3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001750	cellular_component	photoreceptor outer segment
A	0001917	cellular_component	photoreceptor inner segment
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0007601	biological_process	visual perception
A	0007602	biological_process	phototransduction
A	0009966	biological_process	regulation of signal transduction
A	0043204	cellular_component	perikaryon
A	0046872	molecular_function	metal ion binding
A	0051924	biological_process	regulation of calcium ion transport
B	0001750	cellular_component	photoreceptor outer segment
B	0001917	cellular_component	photoreceptor inner segment
B	0005509	molecular_function	calcium ion binding
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0007601	biological_process	visual perception
B	0007602	biological_process	phototransduction
B	0009966	biological_process	regulation of signal transduction
B	0043204	cellular_component	perikaryon
B	0046872	molecular_function	metal ion binding
B	0051924	biological_process	regulation of calcium ion transport
C	0001750	cellular_component	photoreceptor outer segment
C	0001917	cellular_component	photoreceptor inner segment
C	0005509	molecular_function	calcium ion binding
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0007601	biological_process	visual perception
C	0007602	biological_process	phototransduction
C	0009966	biological_process	regulation of signal transduction
C	0043204	cellular_component	perikaryon
C	0046872	molecular_function	metal ion binding
C	0051924	biological_process	regulation of calcium ion transport
D	0001750	cellular_component	photoreceptor outer segment
D	0001917	cellular_component	photoreceptor inner segment
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0007601	biological_process	visual perception
D	0007602	biological_process	phototransduction
D	0009966	biological_process	regulation of signal transduction
D	0043204	cellular_component	perikaryon
D	0046872	molecular_function	metal ion binding
D	0051924	biological_process	regulation of calcium ion transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 501

Chain	Residue
A	ASP110
A	ASP112
A	ASN114
A	THR116
A	GLU121

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 502

Chain	Residue
B	GLU121
B	ASP110
B	ASP112
B	ASN114
B	THR116

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 503

Chain	Residue
C	ASP110
C	ASP112
C	ASN114
C	THR116
C	GLU121

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 504

Chain	Residue
D	ASP110
D	ASP112
D	ASN114
D	THR116
D	GLU121

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DANSDGTLDfkEY

Chain	Residue	Details
A	ASP74-TYR86
A	ASP110-VAL122

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	140
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	140
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	140
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	140
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	4
Details	Modified residue: {"description":"Cysteine sulfenic acid (-SOH)","evidences":[{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25772009","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)