2H8R

Hepatocyte Nuclear Factor 1b bound to DNA: MODY5 Gene Product

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001889	biological_process	liver development
A	0003677	molecular_function	DNA binding
A	0005634	cellular_component	nucleus
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0030073	biological_process	insulin secretion
A	0031016	biological_process	pancreas development
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0001889	biological_process	liver development
B	0003677	molecular_function	DNA binding
B	0005634	cellular_component	nucleus
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0030073	biological_process	insulin secretion
B	0031016	biological_process	pancreas development
B	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. GLgsNlVTevRVYNWFaNrrkeeA

Chain	Residue	Details
A	GLY285-ALA308

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