2H5E
Crystal structure of E.coli polypeptide release factor RF3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006415 | biological_process | translational termination |
| A | 0006449 | biological_process | regulation of translational termination |
| A | 0016149 | molecular_function | translation release factor activity, codon specific |
| A | 0016150 | molecular_function | translation release factor activity, codon nonspecific |
| A | 0019003 | molecular_function | GDP binding |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| A | 1990145 | biological_process | maintenance of translational fidelity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006415 | biological_process | translational termination |
| B | 0006449 | biological_process | regulation of translational termination |
| B | 0016149 | molecular_function | translation release factor activity, codon specific |
| B | 0016150 | molecular_function | translation release factor activity, codon nonspecific |
| B | 0019003 | molecular_function | GDP binding |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 1990145 | biological_process | maintenance of translational fidelity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GDP A 2567 |
| Chain | Residue |
| A | ASP23 |
| A | ASP145 |
| A | ARG146 |
| A | THR258 |
| A | ALA259 |
| A | LEU260 |
| A | ALA24 |
| A | GLY25 |
| A | LYS26 |
| A | THR27 |
| A | THR28 |
| A | HIS92 |
| A | ASN142 |
| A | LYS143 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GDP B 3567 |
| Chain | Residue |
| A | GLY220 |
| A | GLU221 |
| B | ASP23 |
| B | ALA24 |
| B | GLY25 |
| B | LYS26 |
| B | THR27 |
| B | THR28 |
| B | HIS92 |
| B | ASN142 |
| B | LYS143 |
| B | ASP145 |
| B | THR258 |
| B | ALA259 |
| B | LEU260 |
Functional Information from PROSITE/UniProt
| site_id | PS00301 |
| Number of Residues | 16 |
| Details | G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DWmemEKqRGISIttS |
| Chain | Residue | Details |
| A | ASP58-SER73 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | ASP23 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | ASP23 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | HIS92 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | HIS92 |
