Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 801 |
| Chain | Residue |
| A | HOH131 |
| A | HOH621 |
| A | SER1046 |
| A | ARG1049 |
| A | ASP1074 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 803 |
| Chain | Residue |
| A | ARG879 |
| A | TYR880 |
| A | ARG959 |
| B | ALA860 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 804 |
| Chain | Residue |
| A | HOH229 |
| B | ASP887 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 805 |
| Chain | Residue |
| A | HOH81 |
| A | HOH612 |
| A | LYS877 |
| A | ILE907 |
| A | ASN908 |
| A | GLN925 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 806 |
| Chain | Residue |
| A | ASP887 |
| A | HIS888 |
| A | LYS892 |
| A | ALA987 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 1128 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1129 |
| Chain | Residue |
| B | GLN856 |
| B | ARG1096 |
| B | GLN1104 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 1130 |
| Chain | Residue |
| B | HOH52 |
| B | TYR1023 |
| B | THR1024 |
| B | GLN1025 |
| B | TRP1026 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE FLC A 1128 |
| Chain | Residue |
| A | HOH184 |
| A | HOH193 |
| A | HOH221 |
| A | HOH362 |
| A | HIS986 |
| A | TYR989 |
| A | VAL991 |
| A | ARG993 |
| B | HOH669 |
| B | EDO705 |
| B | LYS981 |
| B | ARG993 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 1129 |
| Chain | Residue |
| A | HOH36 |
| A | HOH75 |
| A | HOH616 |
| A | TYR880 |
| A | SER1061 |
| A | ALA1062 |
| B | ASN863 |
| B | ACT1131 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT B 1131 |
| Chain | Residue |
| A | ARG958 |
| A | ACT1129 |
| B | HOH180 |
| B | HOH658 |
| B | HOH659 |
| B | MET862 |
| B | ASN863 |
| B | ILE864 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 701 |
| Chain | Residue |
| B | HOH352 |
| B | GLY914 |
| B | TYR915 |
| B | LYS917 |
| B | ALA920 |
| B | TYR921 |
| B | ARG1049 |
| B | SER1075 |
| B | GLN1078 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 702 |
| Chain | Residue |
| A | HOH42 |
| A | EDO703 |
| A | GLN856 |
| A | ARG1096 |
| A | TYR1101 |
| A | GLN1104 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 703 |
| Chain | Residue |
| A | HOH360 |
| A | EDO702 |
| A | ASN882 |
| A | GLN1104 |
| B | HOH501 |
| B | ASN863 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 704 |
| Chain | Residue |
| A | HOH642 |
| A | GLY914 |
| A | TYR915 |
| A | ALA920 |
| A | TYR921 |
| A | ARG1049 |
| A | SER1075 |
| A | GLN1078 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 705 |
| Chain | Residue |
| A | HOH313 |
| A | SER982 |
| A | THR983 |
| A | VAL991 |
| A | FLC1128 |
| B | HOH669 |
| B | SER982 |
| B | ARG993 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG |
| Chain | Residue | Details |
| A | VAL1058-GLY1068 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | GLU955 | |
| A | CYS1060 | |
| A | ASP1028 | |
| A | THR1067 | |
| A | HIS1059 | |
| A | ARG1066 | |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | GLU955 | |
| B | CYS1060 | |
| B | ASP1028 | |
| B | THR1067 | |
| B | HIS1059 | |
| B | ARG1066 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | CYS1060 | |
| B | ARG1066 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | ASP1028 | |
| A | CYS1060 | |
| A | THR1067 | |
| A | ARG1066 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | ASP1028 | |
| B | CYS1060 | |
| B | THR1067 | |
| B | ARG1066 | |
