2H1K

Crystal structure of the Pdx1 homeodomain in complex with DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LAvmLnLTerHIKIWFqNrrmkwK

Chain	Residue	Details
A	LEU34-LYS57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	118
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
A	ASN1-GLU60
B	ASN1-GLU60

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by PASK => ECO:0000250|UniProtKB:P52946

Chain	Residue	Details
A	THR6
B	THR6

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