2GZH

Crystal Structure of Rab11 in Complex with Rab11-Family Interacting Protein 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0031267	molecular_function	small GTPase binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 901

Chain	Residue
A	THR167
A	THR170
A	HOH604
B	LYS470
B	ASP471
B	ILE474
B	ARG475

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 950

Chain	Residue
A	HOH655
A	HOH658
A	GTP900
A	SER25
A	THR43

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 951

Chain	Residue
A	GLU108
A	HOH648
A	HOH657

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site_id	AC4
Number of Residues	27
Details	BINDING SITE FOR RESIDUE GTP A 900

Chain	Residue
A	SER20
A	GLY21
A	VAL22
A	GLY23
A	LYS24
A	SER25
A	ASN26
A	PHE36
A	ASN37
A	LEU38
A	SER40
A	SER42
A	THR43
A	GLY69
A	ASN124
A	LYS125
A	ASP127
A	LEU128
A	SER154
A	ALA155
A	LEU156
A	HOH565
A	HOH606
A	HOH611
A	HOH655
A	HOH658
A	MG950

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Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL

Chain	Residue	Details
A	VAL14-LEU27

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH, ECO:0007744|PDB:2HV8, ECO:0007744|PDB:5EZ5

Chain	Residue	Details
A	ASP19
A	LYS125
A	ALA155

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH, ECO:0007744|PDB:2HV8, ECO:0007744|PDB:5EZ5

Chain	Residue	Details
A	LEU38

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:1OIW, ECO:0007744|PDB:4D0L, ECO:0007744|PDB:4D0M, ECO:0007744|PDB:5C46, ECO:0007744|PDB:5FBL

Chain	Residue	Details
A	THR67

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N-acetylglycine => ECO:0000269|Ref.11

Chain	Residue	Details
A	THR3

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32974215

Chain	Residue	Details
A	ASP5

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	LEU70

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	GLY21

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