Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2GYY

Structure of aspartate semialdehyde dehydrogenase (ASADH) from Streptococcus pneumoniae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004073	molecular_function	aspartate-semialdehyde dehydrogenase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009085	biological_process	lysine biosynthetic process
A	0009086	biological_process	methionine biosynthetic process
A	0009088	biological_process	threonine biosynthetic process
A	0009089	biological_process	lysine biosynthetic process via diaminopimelate
A	0009097	biological_process	isoleucine biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0019877	biological_process	diaminopimelate biosynthetic process
A	0046983	molecular_function	protein dimerization activity
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
A	0071266	biological_process	'de novo' L-methionine biosynthetic process
B	0000166	molecular_function	nucleotide binding
B	0004073	molecular_function	aspartate-semialdehyde dehydrogenase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009085	biological_process	lysine biosynthetic process
B	0009086	biological_process	methionine biosynthetic process
B	0009088	biological_process	threonine biosynthetic process
B	0009089	biological_process	lysine biosynthetic process via diaminopimelate
B	0009097	biological_process	isoleucine biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0019877	biological_process	diaminopimelate biosynthetic process
B	0046983	molecular_function	protein dimerization activity
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
B	0071266	biological_process	'de novo' L-methionine biosynthetic process
C	0000166	molecular_function	nucleotide binding
C	0004073	molecular_function	aspartate-semialdehyde dehydrogenase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009085	biological_process	lysine biosynthetic process
C	0009086	biological_process	methionine biosynthetic process
C	0009088	biological_process	threonine biosynthetic process
C	0009089	biological_process	lysine biosynthetic process via diaminopimelate
C	0009097	biological_process	isoleucine biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0019877	biological_process	diaminopimelate biosynthetic process
C	0046983	molecular_function	protein dimerization activity
C	0050661	molecular_function	NADP binding
C	0051287	molecular_function	NAD binding
C	0071266	biological_process	'de novo' L-methionine biosynthetic process
D	0000166	molecular_function	nucleotide binding
D	0004073	molecular_function	aspartate-semialdehyde dehydrogenase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009085	biological_process	lysine biosynthetic process
D	0009086	biological_process	methionine biosynthetic process
D	0009088	biological_process	threonine biosynthetic process
D	0009089	biological_process	lysine biosynthetic process via diaminopimelate
D	0009097	biological_process	isoleucine biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0019877	biological_process	diaminopimelate biosynthetic process
D	0046983	molecular_function	protein dimerization activity
D	0050661	molecular_function	NADP binding
D	0051287	molecular_function	NAD binding
D	0071266	biological_process	'de novo' L-methionine biosynthetic process

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
A	GLN155
A	HIS252
A	CYS128

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
B	GLN155
B	HIS252
B	CYS128

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
C	GLN155
C	HIS252
C	CYS128

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
D	GLN155
D	HIS252
D	CYS128

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
A	GLN155
A	CYS128

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
B	GLN155
B	CYS128

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
C	GLN155
C	CYS128

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1brm

Chain	Residue	Details
D	GLN155
D	CYS128

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)