2GWR
Crystal structure of the response regulator protein mtrA from Mycobacterium Tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000156 | molecular_function | phosphorelay response regulator activity |
| A | 0000160 | biological_process | phosphorelay signal transduction system |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032993 | cellular_component | protein-DNA complex |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051701 | biological_process | biological process involved in interaction with host |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 2644 |
| Chain | Residue |
| A | ASP13 |
| A | ASP56 |
| A | MSE58 |
| A | HOH2655 |
| A | HOH2704 |
| A | HOH2727 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 2647 |
| Chain | Residue |
| A | ILE152 |
| A | SER153 |
| A | LEU154 |
| A | PHE159 |
| A | HOH2651 |
| A | HIS143 |
| A | VAL145 |
| A | GLN151 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 2648 |
| Chain | Residue |
| A | ALA164 |
| A | ARG167 |
| A | LYS168 |
| A | PHE173 |
| A | GLN181 |
| A | GLY220 |
| A | VAL221 |
| A | HOH2702 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"4-aspartylphosphate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00169","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16629667","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20223818","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
