2GWD

Crystal structure of plant glutamate cysteine ligase in complex with Mg2+ and L-glutamate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004357	molecular_function	glutamate-cysteine ligase activity
A	0006750	biological_process	glutathione biosynthetic process
A	0042398	biological_process	modified amino acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 515

Chain	Residue
A	GLU107
A	GLU159
A	GLU165
A	GLU521
A	HOH522
A	HOH523

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 516

Chain	Residue
A	ASP250
A	TYR383
A	HOH737
A	PRO170
A	ASN248
A	LEU249

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 517

Chain	Residue
A	LEU307
A	HOH552
A	HOH683

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT A 518

Chain	Residue
A	GLU172
A	GLN176

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 519

Chain	Residue
A	THR281
A	MET291
A	ILE295

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 520

Chain	Residue
A	ARG396
A	PRO489
A	ASN492
A	LEU493
A	HOH586

---

site_id	AC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GLU A 521

Chain	Residue
A	GLU107
A	GLU159
A	THR242
A	CYS243
A	THR244
A	ARG292
A	TRP296
A	ARG387
A	MG515
A	HOH522
A	HOH523
A	HOH661
A	HOH667

---