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2GTF

Crystal structure of nitrophorin 2 complex with pyrimidine

Functional Information from GO Data
ChainGOidnamespacecontents
X0005576cellular_componentextracellular region
X0035821biological_processmodulation of process of another organism
X0042311biological_processvasodilation
X0046872molecular_functionmetal ion binding
X0051381molecular_functionhistamine binding
X0070026molecular_functionnitric oxide binding
X0090729molecular_functiontoxin activity
X0097746biological_processblood vessel diameter maintenance
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE HEM X 201
ChainResidue
XVAL24
XILE120
XLEU132
XP1R202
XHOH310
XHOH375
XHOH376
XHOH415
XHOH431
XPHE27
XTYR38
XSER40
XLEU55
XHIS57
XTYR85
XLYS96
XTYR104

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE P1R X 202
ChainResidue
XILE120
XLEU122
XGLY130
XLEU132
XHEM201

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: proximal binding residue => ECO:0000269|PubMed:10884386, ECO:0007744|PDB:1EUO
ChainResidueDetails
XHIS57

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PDB entries from 2025-06-18

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