2GSE

Crystal Structure of Human Dihydropyrimidinease-like 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0005737	cellular_component	cytoplasm
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0005737	cellular_component	cytoplasm
C	0016787	molecular_function	hydrolase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D	0005737	cellular_component	cytoplasm
D	0016787	molecular_function	hydrolase activity
D	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 1000

Chain	Residue
A	GLN81
A	THR349
A	HOH1089
A	HOH1202
A	HOH1215

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1001

Chain	Residue
B	HOH1175
B	HOH1178
B	THR349
B	HOH1061
B	HOH1099
B	HOH1141

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 1002

Chain	Residue
C	THR349
C	HOH1122
C	HOH1206
C	HOH1222

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA D 1003

Chain	Residue
D	THR349
D	HOH1158
D	HOH1215

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphotyrosine; by FYN => ECO:0000269|PubMed:19652227

Chain	Residue	Details
A	TYR32
B	TYR32
C	TYR32
D	TYR32

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:O08553

Chain	Residue	Details
A	LYS258
B	LYS258
C	LYS258
D	LYS258

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P47942

Chain	Residue	Details
A	SER259
B	SER259
C	SER259
D	SER259

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:O08553

Chain	Residue	Details
A	TYR431
B	TYR431
C	TYR431
D	TYR431

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O08553

Chain	Residue	Details
A	SER465
B	SER465
C	SER465
D	SER465

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