Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003856 | molecular_function | 3-dehydroquinate synthase activity |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016838 | molecular_function | carbon-oxygen lyase activity, acting on phosphates |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003856 | molecular_function | 3-dehydroquinate synthase activity |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016838 | molecular_function | carbon-oxygen lyase activity, acting on phosphates |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO A 601 |
| Chain | Residue |
| A | GLU183 |
| A | HIS246 |
| A | HIS262 |
| A | EXO607 |
| A | HOH695 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO3 A 605 |
| Chain | Residue |
| A | THR247 |
| A | ALA273 |
| A | MET335 |
| A | ILE336 |
| A | HOH721 |
| A | GLU243 |
| A | TYR244 |
| A | GLY245 |
| A | HIS246 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 608 |
| Chain | Residue |
| A | LYS141 |
| A | ASN151 |
| A | LYS322 |
| A | EXO607 |
| B | ARG119 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO B 602 |
| Chain | Residue |
| B | GLU183 |
| B | HIS246 |
| B | HIS262 |
| B | CAK609 |
| B | HOH701 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO3 B 606 |
| Chain | Residue |
| B | GLU243 |
| B | TYR244 |
| B | GLY245 |
| B | HIS246 |
| B | THR247 |
| B | ALA273 |
| B | MET335 |
| B | ILE336 |
| B | HOH716 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD A 603 |
| Chain | Residue |
| A | ASP42 |
| A | GLY44 |
| A | VAL45 |
| A | PRO46 |
| A | ILE49 |
| A | GLU72 |
| A | LYS75 |
| A | GLY103 |
| A | GLY104 |
| A | LEU105 |
| A | ASN108 |
| A | THR128 |
| A | THR129 |
| A | LEU131 |
| A | SER136 |
| A | SER139 |
| A | LYS141 |
| A | ASN151 |
| A | GLN176 |
| A | HOH669 |
| A | HOH696 |
| A | HOH708 |
| A | HOH728 |
| A | HOH751 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE EXO A 607 |
| Chain | Residue |
| A | ASP135 |
| A | GLU183 |
| A | LYS186 |
| A | LYS225 |
| A | GLU235 |
| A | PHE242 |
| A | GLU243 |
| A | HIS246 |
| A | HIS262 |
| A | CO601 |
| A | PO4608 |
| A | HOH616 |
| A | HOH695 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD B 604 |
| Chain | Residue |
| A | ARG119 |
| B | ASP42 |
| B | GLY44 |
| B | VAL45 |
| B | PRO46 |
| B | ILE49 |
| B | GLU72 |
| B | LYS75 |
| B | GLY103 |
| B | GLY104 |
| B | LEU105 |
| B | ASN108 |
| B | THR128 |
| B | THR129 |
| B | LEU131 |
| B | SER136 |
| B | LYS150 |
| B | ASN151 |
| B | GLN176 |
| B | CAK609 |
| B | HOH673 |
| B | HOH693 |
| B | HOH697 |
| B | HOH738 |
| B | HOH745 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE CAK B 609 |
| Chain | Residue |
| B | GLU183 |
| B | LYS186 |
| B | LYS225 |
| B | GLU235 |
| B | PHE242 |
| B | HIS246 |
| B | HIS250 |
| B | HIS262 |
| B | CO602 |
| B | NAD604 |
| B | HOH635 |
| B | HOH701 |
| A | ARG119 |
| B | ASP135 |
| B | LYS141 |
| B | ASN151 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 611 |
| Chain | Residue |
| A | TYR52 |
| A | ARG167 |
| A | ILE168 |
| A | GLU171 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD B 610 |
| Chain | Residue |
| B | ASN278 |
| B | ASN281 |
| B | MET283 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. MISDSGVPDSIV |
| Chain | Residue | Details |
| A | MET39-VAL50 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"17879343","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17879343","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dqs |
| Chain | Residue | Details |
| A | HIS250 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dqs |
| Chain | Residue | Details |
| B | HIS250 | |
