2GIX
Cytoplasmic Domain Structure of Kir2.1 containing Andersen's Mutation R218Q and Rescue Mutation T309K
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005242 | molecular_function | inward rectifier potassium channel activity |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0016020 | cellular_component | membrane |
| B | 0005242 | molecular_function | inward rectifier potassium channel activity |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0016020 | cellular_component | membrane |
| C | 0005242 | molecular_function | inward rectifier potassium channel activity |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0016020 | cellular_component | membrane |
| D | 0005242 | molecular_function | inward rectifier potassium channel activity |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE K A 800 |
| Chain | Residue |
| A | HOH820 |
| A | HOH823 |
| A | HOH942 |
| B | HOH825 |
| B | HOH903 |
| C | HOH832 |
| C | HOH901 |
| D | HOH871 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD D 801 |
| Chain | Residue |
| C | PRO244 |
| D | HIS42 |
| D | GLY43 |
| D | TYR337 |
| D | HOH849 |
| C | SER234 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 802 |
| Chain | Residue |
| A | SER234 |
| A | PRO244 |
| A | HOH882 |
| B | HIS42 |
| B | GLY43 |
| B | TYR337 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD A 803 |
| Chain | Residue |
| A | HIS42 |
| A | GLY43 |
| A | TYR337 |
| A | HOH891 |
| D | LYS233 |
| D | SER234 |
| D | PRO244 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD C 804 |
| Chain | Residue |
| B | SER234 |
| B | PRO244 |
| B | HOH930 |
| C | HIS42 |
| C | GLY43 |
| C | PHE47 |
| C | TYR337 |
