2GGM

Human centrin 2 xeroderma pigmentosum group C protein complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000226	biological_process	microtubule cytoskeleton organization
A	0000278	biological_process	mitotic cell cycle
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005643	cellular_component	nuclear pore
A	0005654	cellular_component	nucleoplasm
A	0005813	cellular_component	centrosome
A	0005814	cellular_component	centriole
A	0005829	cellular_component	cytosol
A	0005929	cellular_component	cilium
A	0006281	biological_process	DNA repair
A	0006289	biological_process	nucleotide-excision repair
A	0006406	biological_process	mRNA export from nucleus
A	0006974	biological_process	DNA damage response
A	0007099	biological_process	centriole replication
A	0007283	biological_process	spermatogenesis
A	0008017	molecular_function	microtubule binding
A	0015031	biological_process	protein transport
A	0031683	molecular_function	G-protein beta/gamma-subunit complex binding
A	0032391	cellular_component	photoreceptor connecting cilium
A	0032465	biological_process	regulation of cytokinesis
A	0032795	molecular_function	heterotrimeric G-protein binding
A	0036064	cellular_component	ciliary basal body
A	0044615	cellular_component	nuclear pore nuclear basket
A	0045177	cellular_component	apical part of cell
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046872	molecular_function	metal ion binding
A	0051028	biological_process	mRNA transport
A	0051301	biological_process	cell division
A	0070390	cellular_component	transcription export complex 2
A	0071942	cellular_component	XPC complex
A	0097225	cellular_component	sperm midpiece
A	0097228	cellular_component	sperm principal piece
A	0097729	cellular_component	9+2 motile cilium
B	0000226	biological_process	microtubule cytoskeleton organization
B	0000278	biological_process	mitotic cell cycle
B	0005509	molecular_function	calcium ion binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005643	cellular_component	nuclear pore
B	0005654	cellular_component	nucleoplasm
B	0005813	cellular_component	centrosome
B	0005814	cellular_component	centriole
B	0005829	cellular_component	cytosol
B	0005929	cellular_component	cilium
B	0006281	biological_process	DNA repair
B	0006289	biological_process	nucleotide-excision repair
B	0006406	biological_process	mRNA export from nucleus
B	0006974	biological_process	DNA damage response
B	0007099	biological_process	centriole replication
B	0007283	biological_process	spermatogenesis
B	0008017	molecular_function	microtubule binding
B	0015031	biological_process	protein transport
B	0031683	molecular_function	G-protein beta/gamma-subunit complex binding
B	0032391	cellular_component	photoreceptor connecting cilium
B	0032465	biological_process	regulation of cytokinesis
B	0032795	molecular_function	heterotrimeric G-protein binding
B	0036064	cellular_component	ciliary basal body
B	0044615	cellular_component	nuclear pore nuclear basket
B	0045177	cellular_component	apical part of cell
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0046872	molecular_function	metal ion binding
B	0051028	biological_process	mRNA transport
B	0051301	biological_process	cell division
B	0070390	cellular_component	transcription export complex 2
B	0071942	cellular_component	XPC complex
B	0097225	cellular_component	sperm midpiece
B	0097228	cellular_component	sperm principal piece
B	0097729	cellular_component	9+2 motile cilium

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 400

Chain	Residue
A	ASP114
A	ASP116
A	THR118
A	LYS120
A	ASN125
A	HOH411

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	GLU156
A	GLU161
A	HOH490
A	ASP150
A	ASP152
A	ASP154

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 402

Chain	Residue
B	ASP114
B	ASP116
B	THR118
B	LYS120
B	ASN125
B	HOH437

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 403

Chain	Residue
B	ASP150
B	ASP152
B	ASP154
B	GLU156
B	GLU161
B	HOH412

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DADGTGTIDvkEL

Chain	Residue	Details
A	ASP41-LEU53
A	ASP150-PHE162

---

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. MIDEADRdG

Chain	Residue	Details
A	MSE145-GLY153

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---