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2G95

Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001774biological_processmicroglial cell activation
A0005125molecular_functioncytokine activity
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0007165biological_processsignal transduction
A0007565biological_processfemale pregnancy
A0007623biological_processcircadian rhythm
A0008286biological_processinsulin receptor signaling pathway
A0009435biological_processNAD biosynthetic process
A0010507biological_processnegative regulation of autophagy
A0014070biological_processresponse to organic cyclic compound
A0014916biological_processregulation of lung blood pressure
A0016757molecular_functionglycosyltransferase activity
A0019363biological_processpyridine nucleotide biosynthetic process
A0032922biological_processcircadian regulation of gene expression
A0042802molecular_functionidentical protein binding
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0047280molecular_functionnicotinamide phosphoribosyltransferase activity
A0048511biological_processrhythmic process
A0048661biological_processpositive regulation of smooth muscle cell proliferation
A0051770biological_processpositive regulation of nitric-oxide synthase biosynthetic process
A0060612biological_processadipose tissue development
A0071456biological_processcellular response to hypoxia
A0071479biological_processcellular response to ionizing radiation
A1901363molecular_functionheterocyclic compound binding
A1904646biological_processcellular response to amyloid-beta
A1905377biological_processresponse to D-galactose
A2000773biological_processnegative regulation of cellular senescence
B0000166molecular_functionnucleotide binding
B0001774biological_processmicroglial cell activation
B0005125molecular_functioncytokine activity
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0007165biological_processsignal transduction
B0007565biological_processfemale pregnancy
B0007623biological_processcircadian rhythm
B0008286biological_processinsulin receptor signaling pathway
B0009435biological_processNAD biosynthetic process
B0010507biological_processnegative regulation of autophagy
B0014070biological_processresponse to organic cyclic compound
B0014916biological_processregulation of lung blood pressure
B0016757molecular_functionglycosyltransferase activity
B0019363biological_processpyridine nucleotide biosynthetic process
B0032922biological_processcircadian regulation of gene expression
B0042802molecular_functionidentical protein binding
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0047280molecular_functionnicotinamide phosphoribosyltransferase activity
B0048511biological_processrhythmic process
B0048661biological_processpositive regulation of smooth muscle cell proliferation
B0051770biological_processpositive regulation of nitric-oxide synthase biosynthetic process
B0060612biological_processadipose tissue development
B0071456biological_processcellular response to hypoxia
B0071479biological_processcellular response to ionizing radiation
B1901363molecular_functionheterocyclic compound binding
B1904646biological_processcellular response to amyloid-beta
B1905377biological_processresponse to D-galactose
B2000773biological_processnegative regulation of cellular senescence
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AARG196
AASP219
AHIS247
AARG311
BARG196
BASP219
BHIS247
BARG311

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING:
ChainResidueDetails
AGLY353
AGLY384
AARG392
BGLY353
BGLY384
BARG392

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P43490
ChainResidueDetails
AMET1
BMET1

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P43490
ChainResidueDetails
ATYR188
BTYR188

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P43490
ChainResidueDetails
ASER472
BSER472

227344

PDB entries from 2024-11-13

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