Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004198 | molecular_function | calcium-dependent cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 365 |
| Chain | Residue |
| A | VAL99 |
| A | GLY101 |
| A | ASP106 |
| A | GLU185 |
| A | HOH422 |
| A | HOH606 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 366 |
| Chain | Residue |
| A | ASP331 |
| A | GLU333 |
| A | HOH432 |
| A | GLU302 |
| A | ASP309 |
| A | MET329 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE D7G A 400 |
| Chain | Residue |
| A | GLN109 |
| A | GLY113 |
| A | ASP114 |
| A | CYS115 |
| A | TRP116 |
| A | SER206 |
| A | GLY207 |
| A | GLY208 |
| A | THR210 |
| A | ILE257 |
| A | GLY271 |
| A | HIS272 |
| A | GLN287 |
| A | ARG288 |
| A | TRP298 |
| A | HOH457 |
| A | HOH641 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGaLGDCWLlAA |
| Chain | Residue | Details |
| A | GLN109-ALA120 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS115 | |
| A | HIS272 | |
| A | ASN296 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; for 75 kDa form => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY27 | |
| Chain | Residue | Details |
| A | THR354 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kfu |
| Chain | Residue | Details |
| A | HIS272 | |
| A | GLN109 | |
| A | ASN296 | |
| A | CYS115 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1kfu |
| Chain | Residue | Details |
| A | HIS272 | |
| A | GLN109 | |
| A | TRP298 | |
| A | ASN296 | |
| A | CYS115 | |
