2G8H

B. halodurans RNase H catalytic domain D192N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 301

Chain	Residue
A	ASP71
A	GLU109
A	ASP132
A	MG302
B	A6
B	HOH55

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 302

Chain	Residue
A	HOH457
A	HOH563
A	HOH565
B	C2
B	HOH55
A	ASP71
A	ASN192
A	MG301

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE VO4 A 401

Chain	Residue
A	TRP168
A	HIS172
A	VO4402
A	VO4403
A	VO4404
A	VO4406

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE VO4 A 402

Chain	Residue
A	LYS121
A	GLU122
A	TRP168
A	VO4401
A	VO4403
A	VO4404
A	VO4405

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE VO4 A 403

Chain	Residue
A	PRO99
A	VO4401
A	VO4402
A	VO4404
A	VO4405
A	VO4406
A	HOH517
A	HOH571

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE VO4 A 404

Chain	Residue
A	GLU122
A	LYS144
A	VO4401
A	VO4402
A	VO4403
A	VO4405
A	VO4406

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE VO4 A 405

Chain	Residue
A	VO4402
A	VO4403
A	VO4404
A	VO4406
A	HOH517

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE VO4 A 406

Chain	Residue
A	LYS144
A	VO4401
A	VO4403
A	VO4404
A	VO4405

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:15989951

Chain	Residue	Details
A	ASP71
A	GLU109
A	ASP132
A	ASN192

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