Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004198 | molecular_function | calcium-dependent cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 365 |
| Chain | Residue |
| A | VAL99 |
| A | GLY101 |
| A | ASP106 |
| A | GLN182 |
| A | GLU185 |
| A | HOH464 |
| A | HOH491 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 366 |
| Chain | Residue |
| A | MET329 |
| A | ASP331 |
| A | GLU333 |
| A | HOH480 |
| A | GLU302 |
| A | ASP309 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 0M6 A 400 |
| Chain | Residue |
| A | GLN109 |
| A | GLY113 |
| A | CYS115 |
| A | TRP116 |
| A | GLY207 |
| A | GLY208 |
| A | CYS209 |
| A | SER251 |
| A | GLY271 |
| A | HIS272 |
| A | HOH412 |
| A | HOH537 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES A 401 |
| Chain | Residue |
| A | GLY110 |
| A | ALA111 |
| A | LEU112 |
| A | GLY113 |
| A | GLU261 |
| A | TRP298 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGaLGDCWLlAA |
| Chain | Residue | Details |
| A | GLN109-ALA120 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 299 |
| Details | Domain: {"description":"Calpain catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00239","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P07384","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kfu |
| Chain | Residue | Details |
| A | HIS272 | |
| A | GLN109 | |
| A | ASN296 | |
| A | CYS115 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1kfu |
| Chain | Residue | Details |
| A | HIS272 | |
| A | GLN109 | |
| A | TRP298 | |
| A | ASN296 | |
| A | CYS115 | |
