Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003874 | molecular_function | 6-pyruvoyltetrahydropterin synthase activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0042559 | biological_process | pteridine-containing compound biosynthetic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 1001 |
| Chain | Residue |
| A | ASN47 |
| A | GLU128 |
| A | GLU129 |
| A | THR130 |
| A | PRO131 |
| A | HOH3019 |
| A | HOH3117 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1002 |
| Chain | Residue |
| A | ASN40 |
| A | GLY43 |
| A | HIS44 |
| A | ARG20 |
| A | CYS38 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 2001 |
| Chain | Residue |
| A | HIS19 |
| A | HIS44 |
| A | HIS46 |
| A | HOH3084 |
| A | HOH3139 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 3001 |
| Chain | Residue |
| A | LYS53 |
| A | TYR123 |
| A | LYS124 |
| A | HOH3116 |
| A | HOH3121 |
Functional Information from PROSITE/UniProt
| site_id | PS00987 |
| Number of Residues | 11 |
| Details | PTPS_1 6-pyruvoyl tetrahydropterin synthase signature 1. CNNsnGHGHNY |
| Chain | Residue | Details |
| A | CYS38-TYR48 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10123","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10123","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b66 |
| Chain | Residue | Details |
| A | CYS38 | |
| A | GLU129 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b66 |
| Chain | Residue | Details |
| A | ASP83 | |
| A | HIS84 | |
