Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003874 | molecular_function | 6-pyruvoyltetrahydropterin synthase activity |
A | 0005739 | cellular_component | mitochondrion |
A | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
A | 0016829 | molecular_function | lyase activity |
A | 0042802 | molecular_function | identical protein binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE NA A 1001 |
Chain | Residue |
A | ASN47 |
A | GLU128 |
A | GLU129 |
A | THR130 |
A | PRO131 |
A | HOH3019 |
A | HOH3117 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA A 1002 |
Chain | Residue |
A | ASN40 |
A | GLY43 |
A | HIS44 |
A | ARG20 |
A | CYS38 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 2001 |
Chain | Residue |
A | HIS19 |
A | HIS44 |
A | HIS46 |
A | HOH3084 |
A | HOH3139 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 3001 |
Chain | Residue |
A | LYS53 |
A | TYR123 |
A | LYS124 |
A | HOH3116 |
A | HOH3121 |
Functional Information from PROSITE/UniProt
site_id | PS00987 |
Number of Residues | 11 |
Details | PTPS_1 6-pyruvoyl tetrahydropterin synthase signature 1. CNNsnGHGHNY |
Chain | Residue | Details |
A | CYS38-TYR48 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS38 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Charge relay system => ECO:0000250 |
Chain | Residue | Details |
A | HIS84 | |
A | GLU129 | |
Chain | Residue | Details |
A | HIS19 | |
A | HIS44 | |
A | HIS46 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b66 |
Chain | Residue | Details |
A | CYS38 | |
A | GLU129 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b66 |
Chain | Residue | Details |
A | ASP83 | |
A | HIS84 | |