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2G64

Structure of Caenorhabditis elegans 6-pyruvoyl tetrahydropterin synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0003874molecular_function6-pyruvoyltetrahydropterin synthase activity
A0005739cellular_componentmitochondrion
A0006729biological_processtetrahydrobiopterin biosynthetic process
A0016829molecular_functionlyase activity
A0042802molecular_functionidentical protein binding
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE NA A 1001
ChainResidue
AASN47
AGLU128
AGLU129
ATHR130
APRO131
AHOH3019
AHOH3117

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 1002
ChainResidue
AASN40
AGLY43
AHIS44
AARG20
ACYS38

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN A 2001
ChainResidue
AHIS19
AHIS44
AHIS46
AHOH3084
AHOH3139

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL A 3001
ChainResidue
ALYS53
ATYR123
ALYS124
AHOH3116
AHOH3121

Functional Information from PROSITE/UniProt
site_idPS00987
Number of Residues11
DetailsPTPS_1 6-pyruvoyl tetrahydropterin synthase signature 1. CNNsnGHGHNY
ChainResidueDetails
ACYS38-TYR48

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10123
ChainResidueDetails
ACYS38

site_idSWS_FT_FI2
Number of Residues2
DetailsACT_SITE: Charge relay system => ECO:0000250
ChainResidueDetails
AHIS84
AGLU129

site_idSWS_FT_FI3
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10123
ChainResidueDetails
AHIS19
AHIS44
AHIS46

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1b66
ChainResidueDetails
ACYS38
AGLU129

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1b66
ChainResidueDetails
AASP83
AHIS84

227111

PDB entries from 2024-11-06

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