2G1H

Structure of E.coli FabD complexed with glycerol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004314	molecular_function	[acyl-carrier-protein] S-malonyltransferase activity
A	0005829	cellular_component	cytosol
A	0006633	biological_process	fatty acid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 310

Chain	Residue
A	GLY10
A	HOH311
A	HOH469
A	GLN11
A	HIS91
A	SER92
A	LEU93
A	ARG117
A	MET121
A	SER200
A	HIS201

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:7768883

Chain	Residue	Details
A	LEU93
A	CYS202

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1mla

Chain	Residue	Details
A	HIS201
A	SER92
A	GLN250

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site_id	MCSA1
Number of Residues	6
Details	M-CSA 291

Chain	Residue	Details
A	GLY12	electrostatic stabiliser, hydrogen bond donor
A	LEU93	activator, covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
A	GLY94	electrostatic stabiliser, hydrogen bond donor
A	GLY118	attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor
A	CYS202	hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, proton acceptor, proton donor
A	LEU251	electrostatic stabiliser, hydrogen bond acceptor, increase basicity

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