2FV8

The crystal structure of RhoB in the GDP-bound state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000281	biological_process	mitotic cytokinesis
A	0001525	biological_process	angiogenesis
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005634	cellular_component	nucleus
A	0005768	cellular_component	endosome
A	0005769	cellular_component	early endosome
A	0005770	cellular_component	late endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005925	cellular_component	focal adhesion
A	0006886	biological_process	intracellular protein transport
A	0006915	biological_process	apoptotic process
A	0007015	biological_process	actin filament organization
A	0007155	biological_process	cell adhesion
A	0007165	biological_process	signal transduction
A	0007264	biological_process	small GTPase-mediated signal transduction
A	0007266	biological_process	Rho protein signal transduction
A	0008333	biological_process	endosome to lysosome transport
A	0010008	cellular_component	endosome membrane
A	0010595	biological_process	positive regulation of endothelial cell migration
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0019003	molecular_function	GDP binding
A	0030154	biological_process	cell differentiation
A	0030334	biological_process	regulation of cell migration
A	0030336	biological_process	negative regulation of cell migration
A	0031902	cellular_component	late endosome membrane
A	0032154	cellular_component	cleavage furrow
A	0043065	biological_process	positive regulation of apoptotic process
A	0045766	biological_process	positive regulation of angiogenesis
A	0045786	biological_process	negative regulation of cell cycle
A	0061154	biological_process	endothelial tube morphogenesis
A	0070062	cellular_component	extracellular exosome
A	0070301	biological_process	cellular response to hydrogen peroxide
A	0071479	biological_process	cellular response to ionizing radiation
A	0098685	cellular_component	Schaffer collateral - CA1 synapse
A	0099159	biological_process	regulation of modification of postsynaptic structure

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GDP A 201

Chain	Residue
A	ASP13
A	LYS118
A	ASP120
A	LEU121
A	SER160
A	ALA161
A	LYS162
A	HOH231
A	HOH237
A	HOH268
A	ALA15
A	CYS16
A	GLY17
A	LYS18
A	THR19
A	CYS20
A	PHE30
A	ALA61

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY12
A	ASP59
A	ASN117

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: ADP-ribosylasparagine; by botulinum toxin => ECO:0000250

Chain	Residue	Details
A	ASN41

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62746

Chain	Residue	Details
A	TYR154

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230 => ECO:0000269|PubMed:24141704

Chain	Residue	Details
A	TYR34

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB => ECO:0000269|PubMed:24905543

Chain	Residue	Details
A	THR37

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	GLN63

---