2FTY
Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004157 | molecular_function | dihydropyrimidinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004157 | molecular_function | dihydropyrimidinase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004157 | molecular_function | dihydropyrimidinase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004157 | molecular_function | dihydropyrimidinase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 601 |
| Chain | Residue |
| A | HIS62 |
| A | HIS64 |
| A | KCX167 |
| A | ASP358 |
| A | ZN602 |
| A | HOH1603 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 602 |
| Chain | Residue |
| A | ZN601 |
| A | HOH1603 |
| A | KCX167 |
| A | HIS199 |
| A | HIS255 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 601 |
| Chain | Residue |
| B | HIS62 |
| B | HIS64 |
| B | KCX167 |
| B | ASP358 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 602 |
| Chain | Residue |
| B | KCX167 |
| B | HIS199 |
| B | HIS255 |
| B | HOH2603 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 601 |
| Chain | Residue |
| C | HIS62 |
| C | HIS64 |
| C | KCX167 |
| C | ASP358 |
| C | HOH3603 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 602 |
| Chain | Residue |
| C | KCX167 |
| C | HIS199 |
| C | HIS255 |
| C | HOH3603 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 601 |
| Chain | Residue |
| D | HIS62 |
| D | HIS64 |
| D | KCX167 |
| D | ASP358 |
| D | HOH4603 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 602 |
| Chain | Residue |
| D | KCX167 |
| D | HIS199 |
| D | HIS255 |
| D | HOH4603 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16517602","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FVK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FVM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"via carbamate group","evidences":[{"source":"PubMed","id":"16517602","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FVK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FVM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16517602","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FVK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PubMed","id":"16517602","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FVK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FVM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| A | ASP358 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| B | ASP358 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| C | ASP358 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| D | ASP358 |
