2FT3

Crystal structure of the biglycan dimer core protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005539	molecular_function	glycosaminoglycan binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0009986	cellular_component	cell surface
A	0019955	molecular_function	cytokine binding
A	0030133	cellular_component	transport vesicle
A	0031012	cellular_component	extracellular matrix
A	0042383	cellular_component	sarcolemma
A	0050840	molecular_function	extracellular matrix binding
A	0060348	biological_process	bone development
A	0061975	biological_process	articular cartilage development
B	0005539	molecular_function	glycosaminoglycan binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0009986	cellular_component	cell surface
B	0019955	molecular_function	cytokine binding
B	0030133	cellular_component	transport vesicle
B	0031012	cellular_component	extracellular matrix
B	0042383	cellular_component	sarcolemma
B	0050840	molecular_function	extracellular matrix binding
B	0060348	biological_process	bone development
B	0061975	biological_process	articular cartilage development
C	0005539	molecular_function	glycosaminoglycan binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0009986	cellular_component	cell surface
C	0019955	molecular_function	cytokine binding
C	0030133	cellular_component	transport vesicle
C	0031012	cellular_component	extracellular matrix
C	0042383	cellular_component	sarcolemma
C	0050840	molecular_function	extracellular matrix binding
C	0060348	biological_process	bone development
C	0061975	biological_process	articular cartilage development
D	0005539	molecular_function	glycosaminoglycan binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0009986	cellular_component	cell surface
D	0019955	molecular_function	cytokine binding
D	0030133	cellular_component	transport vesicle
D	0031012	cellular_component	extracellular matrix
D	0042383	cellular_component	sarcolemma
D	0050840	molecular_function	extracellular matrix binding
D	0060348	biological_process	bone development
D	0061975	biological_process	articular cartilage development
E	0005539	molecular_function	glycosaminoglycan binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0009986	cellular_component	cell surface
E	0019955	molecular_function	cytokine binding
E	0030133	cellular_component	transport vesicle
E	0031012	cellular_component	extracellular matrix
E	0042383	cellular_component	sarcolemma
E	0050840	molecular_function	extracellular matrix binding
E	0060348	biological_process	bone development
E	0061975	biological_process	articular cartilage development
F	0005539	molecular_function	glycosaminoglycan binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0009986	cellular_component	cell surface
F	0019955	molecular_function	cytokine binding
F	0030133	cellular_component	transport vesicle
F	0031012	cellular_component	extracellular matrix
F	0042383	cellular_component	sarcolemma
F	0050840	molecular_function	extracellular matrix binding
F	0060348	biological_process	bone development
F	0061975	biological_process	articular cartilage development

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	CARBOHYD: O-linked (Xyl...) (glycosaminoglycan) serine => ECO:0000269|PubMed:2656687, ECO:0000269|PubMed:2914936

Chain	Residue	Details
A	SER5
E	SER11
F	SER5
F	SER11
A	SER11
B	SER5
B	SER11
C	SER5
C	SER11
D	SER5
D	SER11
E	SER5

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site_id	SWS_FT_FI2
Number of Residues	12
Details	CARBOHYD: O-linked (Xyl...) (glycosaminoglycan) serine => ECO:0000255

Chain	Residue	Details
A	SER144
E	SER162
F	SER144
F	SER162
A	SER162
B	SER144
B	SER162
C	SER144
C	SER162
D	SER144
D	SER162
E	SER144

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site_id	SWS_FT_FI3
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine

Chain	Residue	Details
A	ASN234
B	ASN234
C	ASN234
D	ASN234
E	ASN234
F	ASN234

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site_id	SWS_FT_FI4
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16547006

Chain	Residue	Details
A	ASN275
B	ASN275
C	ASN275
D	ASN275
E	ASN275
F	ASN275

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