Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2FT3

Crystal structure of the biglycan dimer core protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005539	molecular_function	glycosaminoglycan binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0009986	cellular_component	cell surface
A	0019955	molecular_function	cytokine binding
A	0030133	cellular_component	transport vesicle
A	0031012	cellular_component	extracellular matrix
A	0042383	cellular_component	sarcolemma
A	0050840	molecular_function	extracellular matrix binding
A	0060348	biological_process	bone development
A	0061975	biological_process	articular cartilage development
B	0005539	molecular_function	glycosaminoglycan binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0009986	cellular_component	cell surface
B	0019955	molecular_function	cytokine binding
B	0030133	cellular_component	transport vesicle
B	0031012	cellular_component	extracellular matrix
B	0042383	cellular_component	sarcolemma
B	0050840	molecular_function	extracellular matrix binding
B	0060348	biological_process	bone development
B	0061975	biological_process	articular cartilage development
C	0005539	molecular_function	glycosaminoglycan binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0009986	cellular_component	cell surface
C	0019955	molecular_function	cytokine binding
C	0030133	cellular_component	transport vesicle
C	0031012	cellular_component	extracellular matrix
C	0042383	cellular_component	sarcolemma
C	0050840	molecular_function	extracellular matrix binding
C	0060348	biological_process	bone development
C	0061975	biological_process	articular cartilage development
D	0005539	molecular_function	glycosaminoglycan binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0009986	cellular_component	cell surface
D	0019955	molecular_function	cytokine binding
D	0030133	cellular_component	transport vesicle
D	0031012	cellular_component	extracellular matrix
D	0042383	cellular_component	sarcolemma
D	0050840	molecular_function	extracellular matrix binding
D	0060348	biological_process	bone development
D	0061975	biological_process	articular cartilage development
E	0005539	molecular_function	glycosaminoglycan binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0009986	cellular_component	cell surface
E	0019955	molecular_function	cytokine binding
E	0030133	cellular_component	transport vesicle
E	0031012	cellular_component	extracellular matrix
E	0042383	cellular_component	sarcolemma
E	0050840	molecular_function	extracellular matrix binding
E	0060348	biological_process	bone development
E	0061975	biological_process	articular cartilage development
F	0005539	molecular_function	glycosaminoglycan binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0009986	cellular_component	cell surface
F	0019955	molecular_function	cytokine binding
F	0030133	cellular_component	transport vesicle
F	0031012	cellular_component	extracellular matrix
F	0042383	cellular_component	sarcolemma
F	0050840	molecular_function	extracellular matrix binding
F	0060348	biological_process	bone development
F	0061975	biological_process	articular cartilage development

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	138
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	138
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	120
Details	Repeat: {"description":"LRR 4"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	138
Details	Repeat: {"description":"LRR 5"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	144
Details	Repeat: {"description":"LRR 6"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	120
Details	Repeat: {"description":"LRR 7"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	138
Details	Repeat: {"description":"LRR 8"}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	138
Details	Repeat: {"description":"LRR 9"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	132
Details	Repeat: {"description":"LRR 10"}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	174
Details	Repeat: {"description":"LRR 11"}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	12
Details	Glycosylation: {"description":"O-linked (Xyl...) (glycosaminoglycan) serine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine"}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16547006","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)