2FMM

Crystal Structure of EMSY-HP1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
B	0005634	cellular_component	nucleus
C	0005634	cellular_component	nucleus
D	0005634	cellular_component	nucleus
E	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A 601

Chain	Residue
A	LYS155
A	HOH669
A	CYS156
A	PRO157
A	GLN158
A	VAL159
A	HOH621
A	HOH626
A	HOH665
A	HOH666

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 D 602

Chain	Residue
C	HOH674
D	LYS155
D	CYS156
D	PRO157
D	GLN158
D	VAL159
D	HOH633
D	HOH634
D	HOH635
D	HOH652

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 603

Chain	Residue
C	LYS155
C	CYS156
C	PRO157
C	GLN158
C	VAL159
C	HOH678

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 604

Chain	Residue
B	LYS155
B	CYS156
B	PRO157
B	GLN158
B	VAL159
B	HOH635

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	Domain: {"description":"ENT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00476","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Region: {"description":"Interaction with ZMYND11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	232
Details	Domain: {"description":"Chromo 2; shadow subtype","evidences":[{"source":"PROSITE-ProRule","id":"PRU00053","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	28
Details	Site: {"description":"Interacts with the PxVxL motif of TRIM28/TIF1B","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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