2FIB

RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) COMPLEXED TO THE PEPTIDE GLY-PRO-ARG-PRO AT PH 6.0

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007596	biological_process	blood coagulation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 412

Chain	Residue
A	ASP318
A	ASP320
A	PHE322
A	GLY324
A	HOH413
A	HOH414

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Functional Information from PROSITE/UniProt

site_id	PS00514
Number of Residues	13
Details	FIBRINOGEN_C_1 Fibrinogen C-terminal domain signature. WWMnkChaGhlNG

Chain	Residue	Details
A	TRP334-GLY346

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10074346, ECO:0000269|PubMed:19296670, ECO:0000269|PubMed:9016719, ECO:0000269|PubMed:9207064, ECO:0000269|PubMed:9333233, ECO:0000269|PubMed:9628725, ECO:0007744|PDB:1FID

Chain	Residue	Details
A	ASP318
A	ASP320
A	PHE322
A	GLY324

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; in variant Asahi

Chain	Residue	Details
A	ASN308

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CROSSLNK: Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-432)

Chain	Residue	Details
A	GLN398

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-424)

Chain	Residue	Details
A	LYS406

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