2FGE
Crystal structure of presequence protease PreP from Arabidopsis thaliana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0009507 | cellular_component | chloroplast |
| A | 0009570 | cellular_component | chloroplast stroma |
| A | 0009941 | cellular_component | chloroplast envelope |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048046 | cellular_component | apoplast |
| A | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005759 | cellular_component | mitochondrial matrix |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0009507 | cellular_component | chloroplast |
| B | 0009570 | cellular_component | chloroplast stroma |
| B | 0009941 | cellular_component | chloroplast envelope |
| B | 0016485 | biological_process | protein processing |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048046 | cellular_component | apoplast |
| B | 0051603 | biological_process | proteolysis involved in protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 996 |
| Chain | Residue |
| A | HIS77 |
| A | HIS81 |
| A | GLU177 |
| D | THR4 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 996 |
| Chain | Residue |
| B | HIS77 |
| B | HIS81 |
| B | GLU177 |
| E | THR4 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 997 |
| Chain | Residue |
| A | THR202 |
| A | LYS271 |
| A | HOH1389 |
| A | ASN201 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 997 |
| Chain | Residue |
| B | ASN201 |
| B | THR202 |
| B | LYS271 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 998 |
| Chain | Residue |
| A | ASP705 |
| A | HOH1000 |
| A | HOH1001 |
| A | HOH1002 |
| A | HOH1003 |
| A | HOH1004 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 999 |
| Chain | Residue |
| A | ASP510 |
| A | HOH1005 |
| A | HOH1006 |
| A | HOH1007 |
| A | HOH1008 |
| A | HOH1009 |
| A | HOH1010 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 998 |
| Chain | Residue |
| B | ASP705 |
| B | HOH1000 |
| B | HOH1001 |
| B | HOH1002 |
| B | HOH1003 |
| B | HOH1004 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 999 |
| Chain | Residue |
| B | ASP952 |
| B | HOH1005 |
| B | HOH1006 |
| B | HOH1007 |
| B | HOH1008 |
| B | HOH1009 |
| B | HOH1010 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"16601675","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"14617063","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16601675","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2FGE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16601675","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16601675","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FGE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hr6 |
| Chain | Residue | Details |
| A | GLN80 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hr6 |
| Chain | Residue | Details |
| B | GLN80 |
