2FG7
N-succinyl-L-ornithine transcarbamylase from B. fragilis complexed with carbamoyl phosphate and N-succinyl-L-norvaline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006526 | biological_process | L-arginine biosynthetic process |
| C | 0006591 | biological_process | ornithine metabolic process |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0019240 | biological_process | citrulline biosynthetic process |
| C | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| D | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0006526 | biological_process | L-arginine biosynthetic process |
| D | 0006591 | biological_process | ornithine metabolic process |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0016597 | molecular_function | amino acid binding |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| D | 0019240 | biological_process | citrulline biosynthetic process |
| D | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| E | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0006526 | biological_process | L-arginine biosynthetic process |
| E | 0006591 | biological_process | ornithine metabolic process |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0016597 | molecular_function | amino acid binding |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| E | 0019240 | biological_process | citrulline biosynthetic process |
| E | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| X | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| X | 0006520 | biological_process | amino acid metabolic process |
| X | 0006526 | biological_process | L-arginine biosynthetic process |
| X | 0006591 | biological_process | ornithine metabolic process |
| X | 0008652 | biological_process | amino acid biosynthetic process |
| X | 0016597 | molecular_function | amino acid binding |
| X | 0016740 | molecular_function | transferase activity |
| X | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| X | 0019240 | biological_process | citrulline biosynthetic process |
| X | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| Y | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| Y | 0006520 | biological_process | amino acid metabolic process |
| Y | 0006526 | biological_process | L-arginine biosynthetic process |
| Y | 0006591 | biological_process | ornithine metabolic process |
| Y | 0008652 | biological_process | amino acid biosynthetic process |
| Y | 0016597 | molecular_function | amino acid binding |
| Y | 0016740 | molecular_function | transferase activity |
| Y | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| Y | 0019240 | biological_process | citrulline biosynthetic process |
| Y | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| Z | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| Z | 0006520 | biological_process | amino acid metabolic process |
| Z | 0006526 | biological_process | L-arginine biosynthetic process |
| Z | 0006591 | biological_process | ornithine metabolic process |
| Z | 0008652 | biological_process | amino acid biosynthetic process |
| Z | 0016597 | molecular_function | amino acid binding |
| Z | 0016740 | molecular_function | transferase activity |
| Z | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| Z | 0019240 | biological_process | citrulline biosynthetic process |
| Z | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 X 400 |
| Chain | Residue |
| X | ARG35 |
| Y | ARG35 |
| Z | ARG35 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 401 |
| Chain | Residue |
| C | ARG35 |
| D | ARG35 |
| E | ARG35 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SN0 X 345 |
| Chain | Residue |
| X | ARG178 |
| X | LEU180 |
| X | PRO181 |
| X | LYS236 |
| X | LEU275 |
| X | ARG278 |
| X | CP346 |
| X | HOH455 |
| Z | TRP75 |
| Z | PRO90 |
| X | PHE112 |
| X | GLU142 |
| X | HIS176 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP X 346 |
| Chain | Residue |
| X | SER47 |
| X | LEU48 |
| X | ARG49 |
| X | THR50 |
| X | ARG110 |
| X | HIS147 |
| X | GLN150 |
| X | CYS274 |
| X | LEU275 |
| X | ARG302 |
| X | SN0345 |
| Z | TRP75 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SN0 Y 347 |
| Chain | Residue |
| X | PRO90 |
| Y | PHE112 |
| Y | GLU142 |
| Y | HIS176 |
| Y | ARG178 |
| Y | LEU180 |
| Y | PRO181 |
| Y | LYS236 |
| Y | LEU275 |
| Y | ARG278 |
| Y | CP348 |
| Y | HOH356 |
| Y | HOH397 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP Y 348 |
| Chain | Residue |
| X | TRP75 |
| Y | SER47 |
| Y | LEU48 |
| Y | ARG49 |
| Y | THR50 |
| Y | ARG110 |
| Y | HIS147 |
| Y | GLN150 |
| Y | CYS274 |
| Y | LEU275 |
| Y | ARG302 |
| Y | SN0347 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SN0 Z 349 |
| Chain | Residue |
| Y | TRP75 |
| Y | PRO90 |
| Z | PHE112 |
| Z | GLU142 |
| Z | HIS176 |
| Z | ARG178 |
| Z | LEU180 |
| Z | PRO181 |
| Z | LYS236 |
| Z | LEU275 |
| Z | ARG278 |
| Z | CP350 |
| Z | HOH358 |
| Z | HOH364 |
| Z | HOH396 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP Z 350 |
| Chain | Residue |
| Y | TRP75 |
| Z | SER47 |
| Z | LEU48 |
| Z | ARG49 |
| Z | THR50 |
| Z | ARG110 |
| Z | HIS147 |
| Z | GLN150 |
| Z | CYS274 |
| Z | LEU275 |
| Z | ARG302 |
| Z | SN0349 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SN0 C 351 |
| Chain | Residue |
| C | PHE112 |
| C | GLU142 |
| C | HIS176 |
| C | ARG178 |
| C | LEU180 |
| C | PRO181 |
| C | LYS236 |
| C | ARG278 |
| C | CP352 |
| E | TRP75 |
| E | PRO90 |
| E | HOH370 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP C 352 |
| Chain | Residue |
| C | ARG110 |
| C | HIS147 |
| C | GLN150 |
| C | CYS274 |
| C | LEU275 |
| C | ARG302 |
| C | SN0351 |
| E | TRP75 |
| C | SER47 |
| C | LEU48 |
| C | ARG49 |
| C | THR50 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SN0 D 353 |
| Chain | Residue |
| C | TRP75 |
| C | PRO90 |
| D | PHE112 |
| D | GLU142 |
| D | HIS176 |
| D | ARG178 |
| D | LEU180 |
| D | LYS236 |
| D | LEU275 |
| D | ARG278 |
| D | CP354 |
| site_id | BC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP D 354 |
| Chain | Residue |
| C | TRP75 |
| D | SER47 |
| D | LEU48 |
| D | ARG49 |
| D | THR50 |
| D | ARG110 |
| D | HIS147 |
| D | GLN150 |
| D | CYS274 |
| D | LEU275 |
| D | ARG302 |
| D | SN0353 |
| site_id | BC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SN0 E 355 |
| Chain | Residue |
| D | TRP75 |
| D | PRO90 |
| E | PHE112 |
| E | GLU142 |
| E | HIS176 |
| E | ARG178 |
| E | LEU180 |
| E | PRO181 |
| E | LYS236 |
| E | LEU275 |
| E | ARG278 |
| E | CP356 |
| E | HOH387 |
| site_id | BC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP E 356 |
| Chain | Residue |
| D | TRP75 |
| E | SER47 |
| E | LEU48 |
| E | ARG49 |
| E | THR50 |
| E | ARG110 |
| E | HIS147 |
| E | GLN150 |
| E | CYS274 |
| E | LEU275 |
| E | ARG302 |
| E | SN0355 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| X | ARG49 | |
| X | ARG110 | |
| X | HIS147 | |
| X | THR50 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| Y | ARG49 | |
| Y | ARG110 | |
| Y | HIS147 | |
| Y | THR50 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| Z | ARG49 | |
| Z | ARG110 | |
| Z | HIS147 | |
| Z | THR50 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| C | ARG49 | |
| C | ARG110 | |
| C | HIS147 | |
| C | THR50 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| D | ARG49 | |
| D | ARG110 | |
| D | HIS147 | |
| D | THR50 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| E | ARG49 | |
| E | ARG110 | |
| E | HIS147 | |
| E | THR50 |
