2FFH
THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006612 | biological_process | protein targeting to membrane |
| A | 0006614 | biological_process | SRP-dependent cotranslational protein targeting to membrane |
| A | 0008312 | molecular_function | 7S RNA binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0048500 | cellular_component | signal recognition particle |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006612 | biological_process | protein targeting to membrane |
| B | 0006614 | biological_process | SRP-dependent cotranslational protein targeting to membrane |
| B | 0008312 | molecular_function | 7S RNA binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0048500 | cellular_component | signal recognition particle |
| B | 1990904 | cellular_component | ribonucleoprotein complex |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006612 | biological_process | protein targeting to membrane |
| C | 0006614 | biological_process | SRP-dependent cotranslational protein targeting to membrane |
| C | 0008312 | molecular_function | 7S RNA binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0048500 | cellular_component | signal recognition particle |
| C | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 701 |
| Chain | Residue |
| A | MET1 |
| A | ASP296 |
| A | VAL297 |
| A | GLU302 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 702 |
| Chain | Residue |
| A | GLU225 |
| A | GLU323 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD A 703 |
| Chain | Residue |
| A | HIS261 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 704 |
| Chain | Residue |
| A | GLU280 |
| C | LYS151 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 705 |
| Chain | Residue |
| A | ASP97 |
| C | ARG146 |
| C | GLU158 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 750 |
| Chain | Residue |
| A | GLY108 |
| A | SER109 |
| A | GLY110 |
| A | LYS111 |
| A | THR112 |
| B | GLY293 |
| B | GLY295 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD B 701 |
| Chain | Residue |
| B | MET1 |
| B | ASP296 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD B 702 |
| Chain | Residue |
| B | GLU225 |
| B | GLU323 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD B 703 |
| Chain | Residue |
| B | HIS261 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD B 704 |
| Chain | Residue |
| B | GLU280 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 760 |
| Chain | Residue |
| B | GLY108 |
| B | SER109 |
| B | GLY110 |
| B | LYS111 |
| B | THR112 |
| B | THR113 |
| C | GLY295 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD C 701 |
| Chain | Residue |
| C | MET1 |
| C | ASP296 |
| C | GLU302 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD C 702 |
| Chain | Residue |
| C | GLU225 |
| C | GLU323 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD C 703 |
| Chain | Residue |
| C | HIS261 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD C 704 |
| Chain | Residue |
| C | GLU280 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD C 705 |
| Chain | Residue |
| B | ARG169 |
| C | ASP50 |
| C | GLU84 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD C 706 |
| Chain | Residue |
| B | GLU174 |
| C | GLU89 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD C 707 |
| Chain | Residue |
| B | GLU207 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 770 |
| Chain | Residue |
| A | GLY295 |
| C | GLY108 |
| C | SER109 |
| C | GLY110 |
| C | LYS111 |
| C | THR112 |
Functional Information from PROSITE/UniProt
| site_id | PS00300 |
| Number of Residues | 14 |
| Details | SRP54 SRP54-type proteins GTP-binding domain signature. PIyFAGVSEkPegL |
| Chain | Residue | Details |
| A | PRO266-LEU279 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00306","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
