2FAF

The structure of chicken mitochondrial PEPCK.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
A	0004613	molecular_function	phosphoenolpyruvate carboxykinase (GTP) activity
A	0005525	molecular_function	GTP binding
A	0006094	biological_process	gluconeogenesis
A	0017076	molecular_function	purine nucleotide binding
B	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
B	0004613	molecular_function	phosphoenolpyruvate carboxykinase (GTP) activity
B	0005525	molecular_function	GTP binding
B	0006094	biological_process	gluconeogenesis
B	0017076	molecular_function	purine nucleotide binding

Functional Information from PROSITE/UniProt

site_id	PS00505
Number of Residues	9
Details	PEPCK_GTP Phosphoenolpyruvate carboxykinase (GTP) signature. FPSACGKTN

Chain	Residue	Details
A	PHE303-ASN311

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:16819824, ECO:0007744|PDB:2QZY

Chain	Residue	Details
A	ARG105
A	ASN422
A	ARG424
B	ARG105
B	ASN422
B	ARG424

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0007744|PDB:2QZY

Chain	Residue	Details
A	GLY256
B	GLY256

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:16819824, ECO:0007744|PDB:2FAF, ECO:0007744|PDB:2FAH, ECO:0007744|PDB:2QZY

Chain	Residue	Details
A	LYS263
A	HIS283
A	ASP330
B	LYS263
B	HIS283
B	ASP330

---

site_id	SWS_FT_FI4
Number of Residues	22
Details	BINDING: BINDING => ECO:0000269|PubMed:16819824, ECO:0007744|PDB:2FAH

Chain	Residue	Details
A	ALA306
A	PHE549
A	ASN552
B	ALA306
B	GLY308
B	LYS309
B	THR310
B	ASN311
B	PRO356
B	ARG455
B	TRP535
A	GLY308
B	PHE544
B	PHE549
B	ASN552
A	LYS309
A	THR310
A	ASN311
A	PRO356
A	ARG455
A	TRP535
A	PHE544

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16819824, ECO:0007744|PDB:2FAF

Chain	Residue	Details
A	CYS307
B	CYS307

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
A	LYS309
A	HIS283
A	ARG424

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site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
B	LYS309
B	HIS283
B	ARG424

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
A	HIS283
A	ARG424

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site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
B	HIS283
B	ARG424

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