2F8V

Structure of full length telethonin in complex with the N-terminus of titin

Functional Information from GO Data

Chain	GOid	namespace	contents
T	0001756	biological_process	somitogenesis
T	0003009	biological_process	skeletal muscle contraction
T	0003300	biological_process	cardiac muscle hypertrophy
T	0005515	molecular_function	protein binding
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0007512	biological_process	adult heart development
T	0008307	molecular_function	structural constituent of muscle
T	0009887	biological_process	animal organ morphogenesis
T	0014898	biological_process	cardiac muscle hypertrophy in response to stress
T	0030017	cellular_component	sarcomere
T	0030018	cellular_component	Z disc
T	0030049	biological_process	muscle filament sliding
T	0030240	biological_process	skeletal muscle thin filament assembly
T	0030241	biological_process	skeletal muscle myosin thick filament assembly
T	0030674	molecular_function	protein-macromolecule adaptor activity
T	0030916	biological_process	otic vesicle formation
T	0031432	molecular_function	titin binding
T	0031674	cellular_component	I band
T	0035994	biological_process	response to muscle stretch
T	0035995	biological_process	detection of muscle stretch
T	0036122	molecular_function	BMP binding
T	0044325	molecular_function	transmembrane transporter binding
T	0045214	biological_process	sarcomere organization
T	0048646	biological_process	anatomical structure formation involved in morphogenesis
T	0048729	biological_process	tissue morphogenesis
T	0048769	biological_process	sarcomerogenesis
T	0050982	biological_process	detection of mechanical stimulus
T	0051373	molecular_function	FATZ binding
T	0055003	biological_process	cardiac myofibril assembly
T	0055008	biological_process	cardiac muscle tissue morphogenesis
T	0055013	biological_process	cardiac muscle cell development
T	0060048	biological_process	cardiac muscle contraction
T	0060090	molecular_function	molecular adaptor activity
T	0065003	biological_process	protein-containing complex assembly
T	0070080	molecular_function	titin Z domain binding
T	1990733	cellular_component	titin-telethonin complex
Y	0001756	biological_process	somitogenesis
Y	0003009	biological_process	skeletal muscle contraction
Y	0003300	biological_process	cardiac muscle hypertrophy
Y	0005515	molecular_function	protein binding
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0007512	biological_process	adult heart development
Y	0008307	molecular_function	structural constituent of muscle
Y	0009887	biological_process	animal organ morphogenesis
Y	0014898	biological_process	cardiac muscle hypertrophy in response to stress
Y	0030017	cellular_component	sarcomere
Y	0030018	cellular_component	Z disc
Y	0030049	biological_process	muscle filament sliding
Y	0030240	biological_process	skeletal muscle thin filament assembly
Y	0030241	biological_process	skeletal muscle myosin thick filament assembly
Y	0030674	molecular_function	protein-macromolecule adaptor activity
Y	0030916	biological_process	otic vesicle formation
Y	0031432	molecular_function	titin binding
Y	0031674	cellular_component	I band
Y	0035994	biological_process	response to muscle stretch
Y	0035995	biological_process	detection of muscle stretch
Y	0036122	molecular_function	BMP binding
Y	0044325	molecular_function	transmembrane transporter binding
Y	0045214	biological_process	sarcomere organization
Y	0048646	biological_process	anatomical structure formation involved in morphogenesis
Y	0048729	biological_process	tissue morphogenesis
Y	0048769	biological_process	sarcomerogenesis
Y	0050982	biological_process	detection of mechanical stimulus
Y	0051373	molecular_function	FATZ binding
Y	0055003	biological_process	cardiac myofibril assembly
Y	0055008	biological_process	cardiac muscle tissue morphogenesis
Y	0055013	biological_process	cardiac muscle cell development
Y	0060048	biological_process	cardiac muscle contraction
Y	0060090	molecular_function	molecular adaptor activity
Y	0065003	biological_process	protein-containing complex assembly
Y	0070080	molecular_function	titin Z domain binding
Y	1990733	cellular_component	titin-telethonin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 601

Chain	Residue
A	LYS72
A	LYS98
A	ALA99

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 602

Chain	Residue
B	LYS72
B	LYS98
B	ALA99

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 603

Chain	Residue
C	LYS72
C	LYS98
C	ALA99

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 604

Chain	Residue
D	LYS72
D	LYS98
D	ALA99

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 605

Chain	Residue
B	THR114
B	HOH608

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O70548

Chain	Residue	Details
T	SER39
Y	SER39

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