2F8F
Crystal structure of the Y10F mutant of the gluathione s-transferase from schistosoma haematobium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GSH A 212 |
| Chain | Residue |
| A | PHE11 |
| A | HOH255 |
| B | ASP104 |
| A | ARG16 |
| A | TRP41 |
| A | LYS45 |
| A | GLY51 |
| A | ARG52 |
| A | LEU53 |
| A | GLU70 |
| A | SER71 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GSH B 301 |
| Chain | Residue |
| A | ASP104 |
| B | PHE11 |
| B | ARG16 |
| B | TRP41 |
| B | LYS45 |
| B | ARG52 |
| B | LEU53 |
| B | GLU70 |
| B | SER71 |
| B | HOH330 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 164 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CAQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OE8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CAQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2F8F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2F8F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | PHE10 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | PHE10 |
