2F6X
Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with sn-G1P and MPD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006650 | biological_process | glycerophospholipid metabolic process |
| A | 0008654 | biological_process | phospholipid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0046474 | biological_process | glycerophospholipid biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047294 | molecular_function | phosphoglycerol geranylgeranyltransferase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006650 | biological_process | glycerophospholipid metabolic process |
| B | 0008654 | biological_process | phospholipid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0046474 | biological_process | glycerophospholipid biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047294 | molecular_function | phosphoglycerol geranylgeranyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 1GP A 3001 |
| Chain | Residue |
| A | HOH6 |
| A | GLY1194 |
| A | GLY1195 |
| A | GLY1215 |
| A | ASN1216 |
| A | HOH40 |
| A | HOH185 |
| A | HOH219 |
| A | LYS1011 |
| A | TYR1165 |
| A | GLU1167 |
| A | GLY1170 |
| A | GLY1193 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1GP B 3002 |
| Chain | Residue |
| B | HOH21 |
| B | HOH43 |
| B | LYS2011 |
| B | TYR2165 |
| B | GLU2167 |
| B | GLY2170 |
| B | GLY2193 |
| B | GLY2194 |
| B | GLY2195 |
| B | ASN2216 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MPD A 4001 |
| Chain | Residue |
| A | HOH184 |
| A | PRO1065 |
| A | SER1066 |
| A | ASP1067 |
| A | VAL1080 |
| A | PRO1081 |
| A | LYS1095 |
| A | TRP1099 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD B 4002 |
| Chain | Residue |
| B | PRO2065 |
| B | SER2066 |
| B | ASP2067 |
| B | PRO2081 |
| B | LYS2095 |
| B | HIS2096 |
| B | TRP2099 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. AVADSGTDAVMI |
| Chain | Residue | Details |
| A | ALA1025-ILE1036 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00112, ECO:0000269|PubMed:16377641, ECO:0007744|PDB:2F6X |
| Chain | Residue | Details |
| A | LYS1011 | |
| A | TYR1165 | |
| A | GLY1195 | |
| A | GLY1215 | |
| B | LYS2011 | |
| B | TYR2165 | |
| B | GLY2195 | |
| B | GLY2215 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00112 |
| Chain | Residue | Details |
| A | ASP1013 | |
| A | THR1039 | |
| B | ASP2013 | |
| B | THR2039 |
