2F6C

Reaction geometry and thermostability of pyranose 2-oxidase from the white-rot fungus Peniophora sp., Thermostability mutant E542K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0042597	cellular_component	periplasmic space
A	0050233	molecular_function	pyranose oxidase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	35
Details	BINDING SITE FOR RESIDUE FAD A 1625

Chain	Residue
A	VAL52
A	ARG159
A	VAL160
A	GLY163
A	MET164
A	HIS167
A	TRP168
A	THR169
A	CYS170
A	ALA171
A	VAL281
A	GLY53
A	CYS283
A	THR319
A	ALA320
A	HIS324
A	LEU547
A	ASN593
A	THR595
A	HOH1639
A	HOH1657
A	HOH1658
A	GLY55
A	HOH1661
A	HOH1672
A	HOH1689
A	HOH1711
A	HOH1728
A	HOH2220
A	PRO56
A	ILE57
A	ASP76
A	ILE77
A	ILE107
A	THR158

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PG4 A 1626

Chain	Residue
A	SER134
A	PRO144
A	GLU145
A	GLN146
A	ASP147
A	PRO148
A	ARG339

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 1627

Chain	Residue
A	GLY384
A	THR390
A	GLN611
A	THR614

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"E4QP00","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Tele-8alpha-FAD histidine"}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1kdg

Chain	Residue	Details
A	ASN593
A	HIS548

---