Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE VX6 A 514 |
| Chain | Residue |
| A | HOH9 |
| A | GLU316 |
| A | PHE317 |
| A | MET318 |
| A | THR319 |
| A | GLY321 |
| A | LEU370 |
| A | ASP381 |
| A | HOH16 |
| A | GLY249 |
| A | TYR253 |
| A | VAL256 |
| A | ALA269 |
| A | LYS271 |
| A | GLU286 |
| A | THR315 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGGGQYGEVYeGvwkkyslt..........VAVK |
| Chain | Residue | Details |
| A | LEU248-LYS271 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FIHrDLAARNCLV |
| Chain | Residue | Details |
| A | PHE359-VAL371 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP363 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS271 | |
| A | GLU316 | |
| A | LEU248 | |
| Chain | Residue | Details |
| A | SER229 | |
| Chain | Residue | Details |
| A | TYR257 | |
| A | TYR413 | |
| A | TYR253 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by autocatalysis and SRC-type Tyr-kinases => ECO:0000269|PubMed:16912036 |
| Chain | Residue | Details |
| A | TYR393 | |
| Chain | Residue | Details |
| A | SER446 | |
