2F02
Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005988 | biological_process | lactose metabolic process |
| A | 0008443 | molecular_function | phosphofructokinase activity |
| A | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0005988 | biological_process | lactose metabolic process |
| B | 0008443 | molecular_function | phosphofructokinase activity |
| B | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ATP B 410 |
| Chain | Residue |
| B | LYS183 |
| B | SER253 |
| B | GLY254 |
| B | THR257 |
| B | MSE279 |
| B | GLY282 |
| B | MSE283 |
| B | HOH418 |
| B | HOH439 |
| B | HOH468 |
| B | HOH509 |
| B | ASN185 |
| B | HOH512 |
| B | HOH566 |
| B | HOH600 |
| B | SER223 |
| B | LEU224 |
| B | GLY225 |
| B | LYS226 |
| B | GLY228 |
| B | ILE242 |
| B | ILE245 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ATP A 411 |
| Chain | Residue |
| A | LYS183 |
| A | ASN185 |
| A | SER223 |
| A | LEU224 |
| A | GLY225 |
| A | GLY228 |
| A | ILE242 |
| A | ILE245 |
| A | GLY252 |
| A | SER253 |
| A | GLY254 |
| A | ASP255 |
| A | THR257 |
| A | MSE279 |
| A | GLY282 |
| A | MSE283 |
| A | HOH448 |
| A | HOH489 |
| A | HOH537 |
| A | HOH619 |
Functional Information from PROSITE/UniProt
| site_id | PS00583 |
| Number of Residues | 25 |
| Details | PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGkGlNVTrvIhDLGgdviatgvlG |
| Chain | Residue | Details |
| A | GLY36-GLY60 |
| site_id | PS00584 |
| Number of Residues | 14 |
| Details | PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. NPvGSGDatiAGLA |
| Chain | Residue | Details |
| A | ASN249-ALA262 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1tz3 |
| Chain | Residue | Details |
| A | GLY254 | |
| A | ASP255 | |
| A | SER253 | |
| A | GLY252 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1tz3 |
| Chain | Residue | Details |
| B | GLY254 | |
| B | ASP255 | |
| B | SER253 | |
| B | GLY252 |
