2ERX
Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0007165 | biological_process | signal transduction |
| A | 0016020 | cellular_component | membrane |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0007165 | biological_process | signal transduction |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 B 402 |
| Chain | Residue |
| B | GLY16 |
| B | HOH477 |
| B | HOH483 |
| B | LYS20 |
| B | TYR36 |
| B | THR39 |
| B | THR63 |
| B | GLY64 |
| B | SER65 |
| B | GDP401 |
| B | MG403 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 403 |
| Chain | Residue |
| B | SER21 |
| B | THR39 |
| B | GDP401 |
| B | PO4402 |
| B | HOH477 |
| B | HOH483 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 402 |
| Chain | Residue |
| A | GLY16 |
| A | LYS20 |
| A | TYR36 |
| A | THR39 |
| A | THR63 |
| A | GLY64 |
| A | GDP401 |
| A | MG403 |
| A | HOH494 |
| A | HOH495 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | SER21 |
| A | THR39 |
| A | GDP401 |
| A | PO4402 |
| A | HOH494 |
| A | HOH495 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE GDP B 401 |
| Chain | Residue |
| B | GLY17 |
| B | VAL18 |
| B | GLY19 |
| B | LYS20 |
| B | SER21 |
| B | SER22 |
| B | PHE32 |
| B | ARG33 |
| B | GLU34 |
| B | TYR36 |
| B | ASN121 |
| B | LYS122 |
| B | ASP124 |
| B | GLU125 |
| B | SER151 |
| B | ALA152 |
| B | LYS153 |
| B | PO4402 |
| B | MG403 |
| B | HOH407 |
| B | HOH414 |
| B | HOH440 |
| B | HOH477 |
| B | HOH483 |
| B | HOH492 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GDP A 401 |
| Chain | Residue |
| A | GLY17 |
| A | VAL18 |
| A | GLY19 |
| A | LYS20 |
| A | SER21 |
| A | SER22 |
| A | PHE32 |
| A | ARG33 |
| A | GLU34 |
| A | TYR36 |
| A | ASN121 |
| A | LYS122 |
| A | ASP124 |
| A | GLU125 |
| A | SER151 |
| A | ALA152 |
| A | LYS153 |
| A | PO4402 |
| A | MG403 |
| A | HOH445 |
| A | HOH464 |
| A | HOH486 |
| A | HOH494 |
| A | HOH495 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Motif: {"description":"Effector region","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"DEC-2005","submissionDatabase":"PDB data bank","title":"Crystal structure of DIRAS2.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"2ERX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q5PR73","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | SER65 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | SER65 |
