2ER8
Crystal Structure of Leu3 DNA-binding domain complexed with a 12mer DNA duplex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 104 |
| Chain | Residue |
| A | CYS37 |
| A | CYS57 |
| A | CYS60 |
| A | CYS67 |
| A | ZN105 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 105 |
| Chain | Residue |
| A | ZN104 |
| A | CYS37 |
| A | CYS40 |
| A | CYS47 |
| A | CYS57 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 104 |
| Chain | Residue |
| B | CYS37 |
| B | CYS57 |
| B | CYS60 |
| B | CYS67 |
| B | ZN105 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 105 |
| Chain | Residue |
| B | CYS37 |
| B | CYS40 |
| B | CYS47 |
| B | CYS57 |
| B | ZN104 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 105 |
| Chain | Residue |
| C | CYS37 |
| C | CYS57 |
| C | CYS60 |
| C | CYS67 |
| C | ZN106 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 106 |
| Chain | Residue |
| C | CYS37 |
| C | CYS40 |
| C | CYS47 |
| C | CYS57 |
| C | ZN105 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 107 |
| Chain | Residue |
| D | CYS37 |
| D | CYS57 |
| D | CYS60 |
| D | CYS67 |
| D | ZN108 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 108 |
| Chain | Residue |
| D | CYS37 |
| D | CYS40 |
| D | CYS47 |
| D | CYS57 |
| D | ZN107 |
Functional Information from PROSITE/UniProt
| site_id | PS00463 |
| Number of Residues | 32 |
| Details | ZN2_CY6_FUNGAL_1 Zn(2)-C6 fungal-type DNA-binding domain signature. ACveCRqqKskCdaherapep...CtkCakknvp..C |
| Chain | Residue | Details |
| A | ALA36-CYS67 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 120 |
| Details | DNA_BIND: Zn(2)-C6 fungal-type => ECO:0000255|PROSITE-ProRule:PRU00227 |
| Chain | Residue | Details |
| A | CYS37-CYS67 | |
| B | CYS37-CYS67 | |
| C | CYS37-CYS67 | |
| D | CYS37-CYS67 |
