2EJA
Crystal Structure Of Uroporphyrinogen Decarboxylase From Aquifex aeolicus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004853 | molecular_function | uroporphyrinogen decarboxylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006778 | biological_process | porphyrin-containing compound metabolic process |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0004853 | molecular_function | uroporphyrinogen decarboxylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006778 | biological_process | porphyrin-containing compound metabolic process |
| B | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| B | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| B | 0006783 | biological_process | heme biosynthetic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1209 |
| Chain | Residue |
| A | ASP175 |
| A | TYR218 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00218 |
| Chain | Residue | Details |
| A | ARG25 | |
| B | TYR146 | |
| B | SER201 | |
| B | HIS314 | |
| A | PHE44 | |
| A | ASP75 | |
| A | TYR146 | |
| A | SER201 | |
| A | HIS314 | |
| B | ARG25 | |
| B | PHE44 | |
| B | ASP75 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00218 |
| Chain | Residue | Details |
| A | ASP75 | |
| B | ASP75 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uro |
| Chain | Residue | Details |
| A | ASP75 | |
| A | TYR146 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uro |
| Chain | Residue | Details |
| B | ASP75 | |
| B | TYR146 |
