2EFC

Ara7-GDP/AtVps9a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0016192	biological_process	vesicle-mediated transport
B	0000166	molecular_function	nucleotide binding
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005768	cellular_component	endosome
B	0005769	cellular_component	early endosome
B	0005783	cellular_component	endoplasmic reticulum
B	0005886	cellular_component	plasma membrane
B	0006886	biological_process	intracellular protein transport
B	0007033	biological_process	vacuole organization
B	0007034	biological_process	vacuolar transport
B	0010008	cellular_component	endosome membrane
B	0012505	cellular_component	endomembrane system
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0030139	cellular_component	endocytic vesicle
B	0031901	cellular_component	early endosome membrane
B	0032585	cellular_component	multivesicular body membrane
B	0036094	molecular_function	small molecule binding
B	0045324	biological_process	late endosome to vacuole transport
B	0140313	molecular_function	molecular sequestering activity
C	0005085	molecular_function	guanyl-nucleotide exchange factor activity
C	0016192	biological_process	vesicle-mediated transport
D	0000166	molecular_function	nucleotide binding
D	0003924	molecular_function	GTPase activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005768	cellular_component	endosome
D	0005769	cellular_component	early endosome
D	0005783	cellular_component	endoplasmic reticulum
D	0005886	cellular_component	plasma membrane
D	0006886	biological_process	intracellular protein transport
D	0007033	biological_process	vacuole organization
D	0007034	biological_process	vacuolar transport
D	0010008	cellular_component	endosome membrane
D	0012505	cellular_component	endomembrane system
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0030139	cellular_component	endocytic vesicle
D	0031901	cellular_component	early endosome membrane
D	0032585	cellular_component	multivesicular body membrane
D	0036094	molecular_function	small molecule binding
D	0045324	biological_process	late endosome to vacuole transport
D	0140313	molecular_function	molecular sequestering activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GDP B 1200

Chain	Residue
A	ASN180
B	SER25
B	ASN123
B	LYS124
B	ASP126
B	SER153
B	ALA154
B	LYS155
B	HOH1204
B	HOH1208
B	HOH1232
A	ASP185
A	HOH323
B	ASP18
B	GLY20
B	ALA21
B	GLY22
B	LYS23
B	SER24

---

site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GDP D 2200

Chain	Residue
C	ASN180
C	ASP185
C	HOH280
D	ASP18
D	GLY20
D	ALA21
D	GLY22
D	LYS23
D	SER24
D	SER25
D	ASN123
D	LYS124
D	ASP126
D	LEU127
D	SER153
D	ALA154
D	LYS155
D	HOH2208
D	HOH2246

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	288
Details	Domain: {"description":"VPS9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00550","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20833725","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2EFC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Motif: {"description":"Effector region","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20833725","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2EFC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2EFH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	GLN69

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
D	GLN69

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	GLY20

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
D	GLY20

---